Clinical trials in head injury

…, DW Marion, A Marmarou, LF Marshall… - Journal of …, 2002 - liebertpub.com
Traumatic brain injury (TBI) remains a major public health problem globally. In the United
States the incidence of closed head injuries admitted to hospitals is conservatively estimated to …

The contribution of sleep to hippocampus-dependent memory consolidation

L Marshall, J Born - Trends in cognitive sciences, 2007 - cell.com
There is now compelling evidence that sleep promotes the long-term consolidation of
declarative and procedural memories. Behavioral studies suggest that sleep preferentially …

Patient age and outcome following severe traumatic brain injury: an analysis of 5600 patients

…, E Farace, JDF Habbema, LF Marshall… - Journal of …, 2003 - thejns.org
Object. Increasing age is associated with poorer outcome in patients with closed traumatic
brain injury (TBI). It is uncertain whether critical age thresholds exist, however, and the …

[HTML][HTML] A randomized, controlled trial of methylprednisolone or naloxone in the treatment of acute spinal-cord injury: results of the Second National Acute Spinal Cord …

…, L Leo-Summers, J Maroon, LF Marshall… - … England Journal of …, 1990 - Mass Medical Soc
Studies in animals indicate that methylprednisolone and naloxone are both potentially
beneficial in acute spinal-cord injury, but whether any treatment is clinically effective remains …

Administration of methylprednisolone for 24 or 48 hours or tirilazad mesylate for 48 hours in the treatment of acute spinal cord injury: results of the third national acute …

…, M Fazl, M Fehlings, DL Herr, PW Hitchon, LF Marshall… - Jama, 1997 - jamanetwork.com
Objective. —To compare the efficacy of methylprednisolone administered for 24 hours with
methyprednisolone administered for 48 hours or tirilazad mesylate administered for 48 hours …

The role of secondary brain injury in determining outcome from severe head injury

RM Chesnut, LF Marshall, MR Klauber… - 50 Landmark …, 2019 - api.taylorfrancis.com
As triage and resuscitation protocols evolve, it is critical to determine the major extracranial
variables influencing outcome in the setting of severe head injury. We prospectively studied …

Preexisting and de novo humoral immunity to SARS-CoV-2 in humans

…, C Moore, BR Jebson, M Wilkinson, LR Marshall… - Science, 2020 - science.org
Zoonotic introduction of novel coronaviruses may encounter preexisting immunity in humans.
Using diverse assays for antibodies recognizing SARS-CoV-2 proteins, we detected …

Boosting slow oscillations during sleep potentiates memory

L Marshall, H Helgadóttir, M Mölle, J Born - Nature, 2006 - nature.com
There is compelling evidence that sleep contributes to the long-term consolidation of new
memories 1 . This function of sleep has been linked to slow (<1 Hz) potential oscillations, …

A new classification of head injury based on computerized tomography

LF Marshall, SB Marshall, MR Klauber… - Journal of …, 1991 - thejns.org
✓ A new classification of head injury based primarily on information gleaned from the initial
computerized tomography (CT) scan is described. It utilizes the status of the mesencephalic …

Development of the severity of violence against women scales

LL Marshall - Journal of family violence, 1992 - Springer
In response to the need for more sensitive assessment instruments, scales were developed
applicable to the evaluation of male violence against women. Two versions of the Severity of …