[HTML][HTML] Binding of two flaviolin substrate molecules, oxidative coupling, and crystal structure of Streptomyces coelicolor A3 (2) cytochrome P450 158A2

…, M Sundaramoorthy, JA Kalaitzis, LM Reddy… - Journal of Biological …, 2005 - ASBMB
Cytochrome P450 158A2 (CYP158A2) is encoded within a three-gene operon (sco1206-sco1208)
in the prototypic soil bacterium Streptomyces coelicolor A3(2). This operon is widely …

Cytochrome P450 eicosanoids are activators of peroxisome proliferator-activated receptor α

VY Ng, Y Huang, LM Reddy, JR Falck, ET Lin… - Drug Metabolism and …, 2007 - ASPET
Cytochrome P450 (P450) eicosanoids regulate vascular tone, renal tubular transport,
cellular proliferation, and inflammation. Both the CYP4A ω-hydroxylases, which catalyze 20-…

Determination of metmyoglobin reductase activity in bovine skeletal muscles

LM REDDY, CE CARPENTER - Journal of Food Science, 1991 - Wiley Online Library
A novel technique was used to obtain an isolate of skeletal muscle containing MetMb
reductase. The isolate was then used as the enzyme source in an assay procedure to measure …

[BOOK][B] Marine mammals as sentinels of ocean health

LM Reddy, LA Dierauf, FMD Gulland - 2001 - books.google.com
It was January 1958, when Rachel Carson, a marine biologist who had been working with
the US Fish and Wildlife Service, received a letter from Olga Owens Huckins of Duxbury, …

11, 12-epoxyeicosatrienoic acid (11, 12-EET): structural determinants for inhibition of TNF-α-induced VCAM-1 expression

JR Falck, LM Reddy, YK Reddy, M Bondlela… - Bioorganic & medicinal …, 2003 - Elsevier
… Manmohan Reddy a , Y.Krishna Reddy a , Muralidhar Bondlela a , U.Murali Krishna a ,
Yu Ji a , Jianxin Sun b , James K Liao b … X Fang, TL Kaduce, NL Weintraub, S Harmon …

Organocatalytic Selective [3+ 2] Cycloadditions: Synthesis of Functionalized 5-Arylthiomethyl-1, 2, 3-triazoles and 4-Arylthio-1, 2, 3-triazoles

GS Reddy, LM Reddy, AS Kumar… - The Journal of Organic …, 2020 - ACS Publications
An organocatalytic azide–ketone [3 + 2] cycloaddition (OrgAKC) of a variety of 1-aryl-3-(arylthio)propan-2-ones
and 1-alkyl-3-(arylthio)propan-2-ones with different aryl/vinyl/alkyl azides …

Effects of a 20-HETE antagonist and agonists on cerebral vascular tone

…, K Takeuchi, N Miyata, T Ishimoto, LM Reddy… - European journal of …, 2004 - Elsevier
This study examined the effects of a 20-hydroxyeicosatetraenoic acid (20-HETE) antagonist,
20-hydroxyeicosa-6(Z),15(Z)-dienoic acid (WIT002) and two agonists, 4-amino-N-(20-…

14, 15-EET analogs: characterization of structural requirements for agonist and antagonist activity in bovine coronary arteries

KM Gauthier, JR Falck, LM Reddy… - Pharmacological …, 2004 - Elsevier
Arachidonic acid metabolites contribute to the regulation of vascular tone and therefore tissue
blood flow. The vascular endothelium metabolizes arachidonic acid by cytochrome P450 …

[HTML][HTML] Identification of 5, 6-trans-epoxyeicosatrienoic acid in the phospholipids of red blood cells

…, JC McGiff, J Quilley, D Sacerdoti, LM Reddy… - Journal of Biological …, 2004 - ASBMB
A novel eicosanoid, 5,6-trans-epoxy-8Z,11Z,14Z-eicosatrienoic acid (5,6-trans-EET), was
identified in rat red blood cells. Characterization of 5,6-trans-EET in the sn-2 position of the …

Protein phosphatase 2A and Ca2+-activated K+ channels contribute to 11, 12-epoxyeicosatrienoic acid analog mediated mesenteric arterial relaxation

…, L West, MB Field, RE White, LM Reddy… - Prostaglandins & other …, 2007 - Elsevier
Epoxyeicosatrienoic acids (EETs) are considered to be endothelium-derived hyperpolarizing
factors, and are potent activators of the large-conductance, Ca 2+ -activated K + (BK Ca ) …