User profiles for L. WENNING

Leonie Wenning

PhD student, Chalmers University of Technology
Verified email at chalmers.se
Cited by 417

Fatty acid alkyl esters: perspectives for production of alternative biofuels

A Röttig, L Wenning, D Bröker… - Applied microbiology and …, 2010 - Springer
… For example, its energy density (29.2 MJ/L) is similar to that of gasoline (32 MJ/L), whereas
ethanol has a lower energy density (19.6 MJ/L). Furthermore, the research octane number of …

Rapid and durable antiretroviral effect of the HIV-1 integrase inhibitor raltegravir as part of combination therapy in treatment-naive patients with HIV-1 infection: results …

…, LR Gilde, H Wan, MD Miller, LA Wenning… - JAIDS Journal of …, 2007 - journals.lww.com
Background: Raltegravir is an HIV-1 integrase strand-transfer inhibitor with potent in vitro
activity. This study explored the antiretroviral activity and safety of raltegravir in treatment-naive …

Antiretroviral activity, pharmacokinetics, and tolerability of MK-0518, a novel inhibitor of HIV-1 integrase, dosed as monotherapy for 10 days in treatment-naive HIV-1 …

…, R Isaacs, LR Gilde, L Wenning… - JAIDS Journal of …, 2006 - journals.lww.com
… One of these integrase inhibitors, L-000870812, exhibited highly robust antiviral activity
in rhesus macaques infected with an HIV-simian immunodeficiency virus (SIV) chimeric virus, …

[HTML][HTML] Modeling pO2 distributions in the bone marrow hematopoietic compartment. II. Modified Kroghian models

DC Chow, LA Wenning, WM Miller, ET Papoutsakis - Biophysical journal, 2001 - cell.com
Hematopoietic cells of various lineages are organized in distinct cellular architectures in the
bone marrow hematopoietic compartment (BMHC). The homogeneous Kroghian model, …

Simple microscopic theory of Amontons's laws for static friction

MH Müser, L Wenning, MO Robbins - Physical Review Letters, 2001 - APS
… increases linearly with the load L pushing the objects together, … We find that Fs L also
vanishes for disordered surfaces, … Fs L that is independent of contact size and load. This naturally …

Clinical pharmacology profile of raltegravir, an HIV‐1 integrase strand transfer inhibitor

DM Brainard, LA Wenning, JA Stone… - The Journal of …, 2011 - Wiley Online Library
Raltegravir is an HIV‐1 integrase inhibitor approved to treat HIV infection in adults in combination
with other antiretrovirals. Data from healthy volunteers demonstrate that raltegravir is …

Metabolism and disposition in humans of raltegravir (MK-0518), an anti-AIDS drug targeting the human immunodeficiency virus 1 integrase enzyme

…, N Azrolan, M Iwamoto, JA Wagner, LA Wenning - Drug Metabolism and …, 2007 - ASPET
Raltegravir is a potent human immunodeficiency virus 1 (HIV-1) integrase strand transfer
inhibitor that is being developed as a novel anti-AIDS drug. The absorption, metabolism, and …

[HTML][HTML] Modeling pO2 distributions in the bone marrow hematopoietic compartment. I. Krogh's model

DC Chow, LA Wenning, WM Miller, ET Papoutsakis - Biophysical journal, 2001 - cell.com
Human bone marrow (BM) is a tissue of complex architectural organization, which includes
granulopoietic loci, erythroblastic islets, and lymphocytic nodules. Oxygen tension (pO 2 ) is …

Suppression of Niacin‐induced Vasodilation with an Antagonist to Prostaglandin D2 Receptor Subtype 1

…, TM Crumley, F Liu, LA Wenning… - Clinical …, 2007 - Wiley Online Library
Niacin (nicotinic acid) reduces cardiovascular events in patients with dyslipidemia. However,
symptoms associated with niacin‐induced vasodilation (eg., flushing) have limited its use. …

Raltegravir once daily or twice daily in previously untreated patients with HIV-1: a randomised, active-controlled, phase 3 non-inferiority trial

…, J Zhao, AJ Rodgers, ML Rizk, L Wenning… - The Lancet infectious …, 2011 - thelancet.com
Background Twice-daily raltegravir with once-daily tenofovir-emtricitabine is an effective
initial antiretroviral regimen for patients with HIV-1. On the basis of pharmacokinetic data …