User profiles for Lars Olsen

Lars Folke Olsen

- Verified email at get2net.dk - Cited by 8489

Lars Olsen

- Verified email at novozymes.com - Cited by 4935

Lars Rønn Olsen

- Verified email at dtu.dk - Cited by 3060

[HTML][HTML] Deglaciation of fennoscandia

…, JM Harbor, JD Jansen, L Olsen… - Quaternary Science …, 2016 - Elsevier
To provide a new reconstruction of the deglaciation of the Fennoscandian Ice Sheet, in the
form of calendar-year time-slices, which are particularly useful for ice sheet modelling, we …

A multifractal formalism

L Olsen - Advances in mathematics, 1995 - Elsevier
Let X be a metric space and μ a Borel probability measure on X. For q, t ∈ R and E ⊆ X
write [formula]Then H q, t μ and P q, t μ are Borel measures − H q, t μ is a multifractal …

Study on the binding of Thioflavin T to β-sheet-rich and non-β-sheet cavities

M Groenning, L Olsen, M van de Weert, JM Flink… - Journal of structural …, 2007 - Elsevier
Amyloid fibril formation plays a role in more than 20 diseases including Alzheimer’s disease.
In vitro detection of these fibrils is often performed using Thioflavin T (ThT), though the ThT …

Self-affine multifractal Sierpinski sponges in ℝd

L Olsen - Pacific journal of mathematics, 1998 - msp.org
We study self-affine multifractals in ℝ d using the formalism introduced in [Olsen, A multifractal
formalism, Advances in Mathematics, 116 (1996), 82-196]. We prove that new multifractal …

Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial

…, L Elagina, W Zhang, O Olive, C McCluskey, LR Olsen… - Nature, 2019 - nature.com
Neoantigens, which are derived from tumour-specific protein-coding mutations, are exempt
from central tolerance, can generate robust immune responses 1 , 2 and can function as …

Chaos versus noisy periodicity: alternative hypotheses for childhood epidemics

LF Olsen, WM Schaffer - Science, 1990 - science.org
Whereas case rates for some childhood diseases (chickenpox) often vary according to an
almost regular annual cycle, the incidence of more efficiently transmitted infections such as …

Personal neoantigen vaccines induce persistent memory T cell responses and epitope spreading in patients with melanoma

…, N Hacohen, KJ Livak, SA Shukla, LR Olsen… - Nature medicine, 2021 - nature.com
Personal neoantigen vaccines have been envisioned as an effective approach to induce,
amplify and diversify antitumor T cell responses. To define the long-term effects of such a …

SMARTCyp: a 2D method for prediction of cytochrome P450-mediated drug metabolism

…, J Zaretzki, C Breneman, L Olsen - ACS medicinal …, 2010 - ACS Publications
SMARTCyp is an in silico method that predicts the sites of cytochrome P450-mediated
metabolism of druglike molecules. The method is foremost a reactivity model, and as such, it …

[PDF][PDF] Progressive immune dysfunction with advancing disease stage in renal cell carcinoma

…, KJ Livak, DF McDermott, SA Shukla, LR Olsen… - Cancer Cell, 2021 - cell.com
The tumor immune microenvironment plays a critical role in cancer progression and response
to immunotherapy in clear cell renal cell carcinoma (ccRCC), yet the composition and …

Chaos in an enzyme reaction

LF Olsen, H Degn - Nature, 1977 - nature.com
DYNAMIC systems are usually thought to have either monotonic or periodic behaviour.
Although the possibility of other types of behaviour has been recognised for many years, the …