Objective Gut microbiota metabolises bile acids (BA). As dysbiosis has been reported in
inflammatory bowel diseases (IBD), we aim to investigate the impact of IBD-associated …

Background Patients with primary biliary cholangitis who have an inadequate response to
therapy with ursodeoxycholic acid are at high risk for disease progression. Fibrates, which are …

Background & Aims Alcoholic liver disease (ALD) is a leading cause of liver failure and
mortality. In humans, severe alcoholic hepatitis is associated with key changes to intestinal …

Many regulatory pathways are involved in liver regeneration after partial hepatectomy (PH)
to initiate growth, protect liver cells, and sustain functions of the remnant liver. Bile acids (BAs)…

The role of bile acids in cell metabolism, membrane biology and cell signaling is increasingly
recognized, thus making necessary a robust and versatile technique to extract, separate …

Objective Microsomal prostaglandin E synthase 1 (mPGES‐1) is the final enzyme of the
cascade that produces prostaglandin E 2 (PGE 2 ), a key actor in arthritis. To study mPGES‐1 …

The current pandemic of coronavirus disease (COVID) 2019 constitutes a global public
health issue. Regarding the emerging importance of the gut-lung axis in viral respiratory …

Context: Bile acids and fibroblast growth factor 19 (FGF19) have been suggested as key
mediators of the improvements in glucose metabolism after Roux-en-Y gastric bypass (RYGB). …

Background Intestinal microbiota plays an important role in bile acid homeostasis. Aim To
study the structure of the intestinal microbiota and its function in bile acid homeostasis in …

The hereditary spastic paraplegias are an expanding and heterogeneous group of disorders
characterized by spasticity in the lower limbs. Plasma biomarkers are needed to guide the …