User profiles for M. S. Landi

Margaret Landi

Chief of Animal Welfare, Ethics and Strategy, GSK Pharmaceuticals
Verified email at gsk.com
Cited by 512

Effects of shipping on the immune function in mice.

MS Landi, JW Kreider, CM Lang… - American journal of …, 1982 - europepmc.org
The effect of shipping stress on immunologic functions was examined in mice. The mice were
shipped either by truck or by plane, 2 of the most common modes for transport of animals. …

The effects of four types of restraint on serum alanine aminotransferase and aspartate aminotransferase in the Macaca fascicularis

MS Landi, JT Kissinger, SA Campbell… - Journal of the …, 1990 - journals.sagepub.com
To determine the effect of restraint on selected clinical laboratory parameters, cynomolgus
monkeys were continuously restrained for 60 and 120 minutes in a restraining box, a restraint …

Some effects of limited exercise on purpose-bred beagles.

…, HC Hughes, HE Griffin, MS Landi… - American Journal of …, 1988 - europepmc.org
Amendments to the Animal Welfare Act (PL 99-198) require that an exercise program for dogs
be established by the attending veterinarian. A 6-week study was conducted to determine …

Vascular-access-port implantation for serial blood sampling in conscious swine.

MB Bailie, SK Wixson, MS Landi - Laboratory animal science, 1986 - europepmc.org
A method to simplify serial venous blood sampling in miniature pigs was developed. Jugular
vein Vascular-Access-Ports (VAP) were implanted in four animals. The mean functional …

Animal care best practices for regulatory testing

D Fillman-Holliday, MS Landi - ILAR journal, 2002 - academic.oup.com
Best practices result from a partnership between law, science, and the people working with
the animals on regulated studies. In an ideal setting, people working with animals observe …

Comparison of antibody response by use of synthetic adjuvant system and Freund complete adjuvant in rabbits

…, ME Graichen, BR Conway, MS Landi… - American journal of …, 1991 - Am Vet Med Assoc
Two commercially available synthetic adjuvant systems, trehalose dimycolate ( tdm ) and tdm
+ monophosphoryl lipid A ( mpl ), were compared with Freund complete adjuvant ( fca ) for …

Effects of caging type and group size on selected physiologic variables in rats

FM Rock, MS Landi, HC Hughes… - Journal of the American …, 1997 - ingentaconnect.com
Considerable debate exists over the effects that various housing conditions have on rodents.
We implanted male Sprague Dawley rats with telemetry devices to evaluate the effects of …

Sex effects across the lifespan in women with multiple sclerosis

…, D Jacobs, V Jokubaitis, D Landi… - Therapeutic …, 2020 - journals.sagepub.com
… in women with MS. Here, we review sex effects across the lifespan in women with MS,
including the effect of sex on MS susceptibility, effects of pregnancy on MS disease activity, and …

Consideration and checkboxes: incorporating ethics and science into the 3Rs

MS Landi, AJ Shriver, A Mueller - Journal of the American …, 2015 - ingentaconnect.com
… A rote following of instructions could lead IACUC members to miss potential changes that
would enhance the welfare of the animals. Second, the checkbox approach can lead to a bias …

Ovarian reserve in patients with multiple sclerosis: A systematic review and meta‐analysis

…, A Conforti, GG Iorio, V Simeon, D Landi… - … of Gynecology & …, 2023 - Wiley Online Library
… sions, is the most common course of MS, often diagnosed at onset in the majority of … MS to
plan their parental life similarly to women without MS.The protective role of pregnancy on MS