A gas-liquid-chromatographic procedure for separating a wide range of metabolites occurring in urine or tissue extracts

CE Dalgliesh, EC Horning, MG Horning… - Biochemical …, 1966 - portlandpress.com
1. A gas-liquid-chromatographic procedure is described which permits separation and
identification on the same chromatogram of a wide range of substances occurring in urine or …

New picogram detection system based on a mass spectrometer with an external ionization source at atmospheric pressure

EC Horning, MG Horning, DI Carroll, I Dzidic… - Analytical …, 1973 - ACS Publications
A novel mass spectrometer with an external ionization source can be used to detect picogram
quantities of compounds of biologic interest. The source contains a 63Ni foil, and is at …

Metabolic profiles: gas-phase methods for analysis of metabolites

EC Horning, MG Horning - Clinical chemistry, 1971 - academic.oup.com
Multicomponent analyses were carried out for three types of urinary constituents: steroids,
acids, and drugs and drug metabolites. The methods were based on gas-phase analytical …

Atmospheric pressure ionization (API) mass spectrometry. Solvent-mediated ionization of samples introduced in solution and in a liquid chromatograph effluent stream

…, I Dzidic, KD Haegele, MG Horning… - Journal of …, 1974 - academic.oup.com
Atmospheric pressure ionization (API) mass spectrometry is a novel form of mass spectrometry
in which ions are generated in a reaction chamber external to the low pressure region of …

Subpicogram detection system for gas phase analysis based upon atmospheric pressure ionization (API) mass spectrometry

…, RN Stillwell, MG Horning, EC Horning - Analytical …, 1974 - ACS Publications
A new atmospheric pressure ionization source of simpli-fied and improved design, for use
with a modified quad-rupole mass spectrometer, is described. Ionization reactions, initiated by …

Human metabolic profiles obtained by GC and GC/MS

EC Horning, MG Horning - Journal of Chromatographic Science, 1971 - academic.oup.com
Metabolic profiles can be obtained by gas phase analytical methods for many types of human
metabolic products. These include urinary steroids, urinary and blood sugars and sugar …

Methone derivatives of aldehydes

EC Horning, MG Horning - The Journal of Organic Chemistry, 1946 - ACS Publications
It has been known for a long time that a variety of dehydration conditions will convert the
normal derivatives (I) into octahydroxanthenes (II). Heating in acetic anhydride is the usual …

[PDF][PDF] Metabolism of carbamazepine.

K Lertratanangkoon, MG Horning - Drug Metabolism and Disposition, 1982 - Citeseer
Thirty-two metabolites of carbamazepine, In addition to the 10, 11-epoxide, have been isolated
from enzymatlcally hydrolyzed urine by HPLC and identified by gas-chromatographic and …

Use of saliva in therapeutic drug monitoring.

MG Horning, L Brown, J Nowlin… - Clinical …, 1977 - academic.oup.com
We measured the concentrations of phenobarbital, phenytoin, primidone, ethosuximide,
antipyrine, and caffeine in paired samples of saliva and plasma by gas chromatograph-mass …

Liquid chromatograph—mass spectrometer—computer analytical systems: a continuous-flow system based on atmospheric pressure ionization mass spectrometry

…, DI Carroll, I Dzidic, KD Haegele, MG Horning… - … of Chromatography A, 1974 - Elsevier
Atmospheric pressure ionization (API) mass spectrometry is a novel form of mass spectrometry
in which ions are generated in a reaction chamber external to the low-pressure region of …