Glioblastomas are the most common form of malignant primary brain tumor and an important
cause of morbidity and mortality. In recent years there have been important advances in …

Resistance to alkylating agents via direct DNA repair by O(6)-methylguanine methyltransferase
(MGMT) remains a significant barrier to the successful treatment of patients with …

CNS metastases are the most common cause of malignant brain tumours in adults. Historically,
patients with brain metastases have been excluded from most clinical trials, but their …

… For this we divide the interval S into m equal parts. … the probabilities in various intervals
of length S/m obtained by dividing S into m equal parts are mutually independent, we arrive at …

Background Concurrent treatment with temozolomide and radiotherapy followed by maintenance
temozolomide is the standard of care for patients with newly diagnosed glioblastoma. …

Background Brain metastases occur in up to 40% of all patients with systemic cancer. We
aimed to assess whether stereotactic radiosurgery provided any therapeutic benefit in a …

… Employment or Leadership Position: Minesh Mehta, Pharmacyclics (C), Apogenix (C)
Consultant or Advisory Role: John Suh, Abbott (C); Nancy Lin, GlaxoSmithKline (C) …

Classi cation is an important data mining problem. Although classi cation is a wellstudied
problem, most of the current classication algorithms require that all or a portion of the the entire …

… In the PCV arm, four cycles were given every 6 weeks before RT, as follows: lomustine
130 mg/m 2 orally on day 1; procarbazine 75 mg/m 2 orally daily, days 8 through 21; and …

… where, cost(DIM) is the cost, in number of bits, of encoding the data given a model M and
cost(M) is the cost of encoding the model M. In the context of the decision tree classifiers, the …