Recent work with approaches like recombinant mutants and X-ray crystallography has
given much new information about the ligand-binding properties of human serum albumin (HSA). …

One of the important characteristics of cyclodextrins is the formation of an inclusion complex
with a variety of drug molecules in solution and in the solid state. As a consequence of …

Background Human serum albumin acts as a reservoir and transport protein for endogenous
(eg fatty acids or bilirubin) and exogenous compounds (eg drugs or nutrients) in the blood. …

… in the complex with thyroxine, a significantly larger molecule (M r 777 Da) 6 (Figure 3(d)
and (e)). For CMPF and the drugs used in this study (M r ∼310 Da) the greatest movement is …

The accumulation of p-cresyl sulfate (PCS), a uremic toxin, is associated with the mortality
rate of chronic kidney disease patients; however, the biological functions and the mechanism …

Gene manipulation techniques open up the possibility of making recombinant human serum
albumin (rHSA) or mutants with desirable therapeutic properties and for protein fusion …

… 25 Maruyama, T., Lin, CC, Yamasaki, K., Miyoshi, T., Imai, T., Yamasaki, M. and Otagiri, M.
(1993) … and Otagiri, M. (1993) Study of interaction of carprofen and its enantiomers with human …

… With sodium phosphate dibasic and sodium phosphate monobasic, 0.067 M phosphate …
The mobile phase for iodipamide was 0.1 M acetate buffer (pH 5.5)-acetonitrile (90:10, v/v) on a …

Purpose. The purpose of this study was the classification and identification of drug binding
sites on albumins from several species in order to understand species differences of both …

… Otagiri M, Masuda K, Imai T, Imamura Y and Yamasaki M, Binding of pirprofen to human
serum albumin studied by dialysis and spectroscopy techniques. Biochem Pharmacol 38: 1-7, …