User profiles for Mahmoud Sharkawi
 | Mahmoud SharkawiAssistant Professor, Al Ain University Verified email at aau.ac.ae Cited by 5 |
Role of CYP2B6 and CYP3A4 in the In VitroN-Dechloroethylation of (R)-and (S)-Ifosfamide in Human Liver Microsomes
CP Granvil, A Madan, M Sharkawi, A Parkinson… - Drug Metabolism and …, 1999 - ASPET
The central nervous system toxicity of ifosfamide (IFF), a chiral antineoplastic agent, is thought
to be dependent on itsN-dechloroethylation by hepatic cytochrome P-450 (CYP) enzymes. …
to be dependent on itsN-dechloroethylation by hepatic cytochrome P-450 (CYP) enzymes. …
Synthetic polarization maps of an outflow zone from magnetohydrodynamic simulations
The canonical theory of star formation in a magnetized environment predicts the formation of
hourglass-shaped magnetic fields during the prestellar collapse phase. In protostellar cores…
hourglass-shaped magnetic fields during the prestellar collapse phase. In protostellar cores…
In vivo inhibition of liver alcohol dehydrogenase by ethanol administration
M Sharkawi - Life sciences, 1984 - Elsevier
The activity of liver alcohol dehydrogenase (LADH) from rats sacrificed two hours after the
administration of ethanol 3, 4 or 5 g/kg intraperitoneally was significantly inhibited compared …
administration of ethanol 3, 4 or 5 g/kg intraperitoneally was significantly inhibited compared …
Inhibition of alcohol dehydrogenase by dimethyl formamide and dimethyl sulfoxide
M Sharkawi - Toxicology Letters, 1979 - Elsevier
Dimethyl formamide (DMF) and dimethyl sulfoxide (DMSO) inhibit mouse liver alcohol
dehydrogenase (LADH) in vitro. The inhibition is “uncompetitive” with both DMF and DMSO, …
dehydrogenase (LADH) in vitro. The inhibition is “uncompetitive” with both DMF and DMSO, …
The Magnetic Field of Protostar-Disk-Outflow Systems
M Sharkawi - 2023 - search.proquest.com
Recent observations of protostellar cores reveal complex magnetic field configurations that
are distorted in the innermost disk region. Unlike the prestellar phase, where the magnetic …
are distorted in the innermost disk region. Unlike the prestellar phase, where the magnetic …
Relationship between acetylcholine synthesis and its concentration in rat cerebral cortex
M Sharkawi, MP Schulman - British Journal of Pharmacology, 1969 - ncbi.nlm.nih.gov
The synthesis of carbon-14 labelled acetylcholine (14 C-ACh) from carbon-14 uniformly
labelled glucose (UL 14 C-glucose) under different conditions has been studied.
labelled glucose (UL 14 C-glucose) under different conditions has been studied.
Inhibition of alcohol dehydrogenase by disulfiram; possible relation to the disulfiram-ethanol reaction
M Sharkawi - Life Sciences, 1980 - Elsevier
Disulfiram inhibited mouse and rat liver alcohol dehydrogenase (LADH) in vitro . Inhibition of
LADH by disulfiram appears to be non-competitive. The inhibition constants (Ki) were about …
LADH by disulfiram appears to be non-competitive. The inhibition constants (Ki) were about …
Effects of caffeine and cyclic adenosine 3′, 5′-monophosphate on adenosine triphosphate-dependent calcium uptake by lysed brain synaptosomes
K Mekhail-Ishak, PA Lavoie, M Sharkawi - Brain research, 1987 - Elsevier
The adenosine triphosphate-dependent calcium uptake by endoplasmic reticulum elements
of lysed synaptosomes from rat brain cortex was studied. Caffeine exhibited a biphasic …
of lysed synaptosomes from rat brain cortex was studied. Caffeine exhibited a biphasic …
Antagonism by physostigmine of the “running fit” caused by levorphanol, a morphine congener, in mice
M Sharkawi, A Goldstein - British Journal of Pharmacology, 1969 - ncbi.nlm.nih.gov
Methods Male Swiss-Webster mice (20-30 g) were placed, in groups of three, in rectangular
cages (13 x 28 cm, 13 cm high) with wire-screen floors. The running activity was measured …
cages (13 x 28 cm, 13 cm high) with wire-screen floors. The running activity was measured …
Pharmacological and metabolic interactions between ethanol and methyl n-butyl ketone, methyl isobutyl ketone, methyl ethyl ketone, or acetone in mice
J Cunningham, M Sharkawi, GL Plaa - Fundamental and Applied …, 1989 - Elsevier
Methyl n-butyl ketone (MnBK), methyl isobutyl ketone (MIBK), methyl ethyl ketone (MEK), and
acetone are widely used industrial solvents to which certain groups of workers are exposed…
acetone are widely used industrial solvents to which certain groups of workers are exposed…