User profiles for Majorie B. M. van Duursen

Majorie van Duursen

Vrije Universiteit
Verified email at vu.nl
Cited by 2184

Modulation of estrogen synthesis and metabolism by phytoestrogens in vitro and the implications for women's health

MBM Van Duursen - Toxicology Research, 2017 - academic.oup.com
Phytoestrogens are increasingly used as dietary supplements due to their suggested health
promoting properties, but also by women for breast enhancement and relief of menopausal …

[HTML][HTML] Experimental human placental models for studying uptake, transport and toxicity of micro-and nanoplastics

HM Dusza, J van Boxel, MBM van Duursen… - Science of The Total …, 2023 - Elsevier
Micro- and nanoplastics (MNPs) are ubiquitous in the environment and have recently been
found in human lungs, blood and placenta. However, data on the possible effects of MNPs on …

[HTML][HTML] Safeguarding female reproductive health against endocrine disrupting chemicals—The FREIA project

MBM van Duursen, J Boberg, S Christiansen… - International journal of …, 2020 - mdpi.com
Currently available test methods are not well-suited for the identification of chemicals that
disturb hormonal processes involved in female reproductive development and function. This …

Structural bisphenol analogues differentially target steroidogenesis in murine MA-10 Leydig cells as well as the glucocorticoid receptor

…, TFH Bovee, AH Piersma, MBM van Duursen - Toxicology, 2015 - Elsevier
Although much information on the endocrine activity of bisphenol A (BPA) is available, a proper
human hazard assessment of analogues that are believed to have a less harmful toxicity …

Endocrine Disruptors Differentially Target ATP-Binding Cassette Transporters in the Blood-Testis Barrier and Affect Leydig Cell Testosterone Secretion In Vitro

…, M van den Berg, MBM van Duursen… - toxicological …, 2013 - academic.oup.com
Endocrine-disrupting chemicals (EDCs) are considered to cause testicular toxicity primarily
via interference with steroid hormone function. Alternatively, EDCs could possibly exert their …

[HTML][HTML] A new highly specific and robust yeast androgen bioassay for the detection of agonists and antagonists

…, ARM Hamers, MBM van Duursen… - Analytical and …, 2007 - Springer
Public concern about the presence of natural and anthropogenic compounds which affect
human health by modulating normal endocrine functions is continuously growing. Fast and …

Anti-aromatase effect of resveratrol and melatonin on hormonal positive breast cancer cells co-cultured with breast adipose fibroblasts

S Chottanapund, MBM Van Duursen, P Navasumrit… - Toxicology in Vitro, 2014 - Elsevier
Targeting the estrogen pathway has been proven effective in the treatment for estrogen
receptor positive breast cancer. There are currently two common groups of anti-estrogenic …

Genistein induces breast cancer-associated aromatase and stimulates estrogen-dependent tumor cell growth in in vitro breast cancer model

MBM van Duursen, SM Nijmeijer, ES De Morree… - Toxicology, 2011 - Elsevier
In breast cancer, the interaction between estrogen-producing breast adipose fibroblasts (BAFs)
and estrogen-dependent epithelial tumor cells is pivotal. Local estrogen production is …

Potential health and environmental risks of three-dimensional engineered polymers

…, S Le Gac, F Bray, MBM Van Duursen… - … science & technology …, 2018 - ACS Publications
Polymer engineering, such as in three-dimensional (3D) printing, is rapidly gaining popularity,
not only in the scientific and medical fields but also in the community in general. However, …

[HTML][HTML] Conazole fungicides inhibit Leydig cell testosterone secretion and androgen receptor activation in vitro

…, AH Piersma, M van den Berg, MBM van Duursen - Toxicology reports, 2014 - Elsevier
Conazole fungicides are widely used in agriculture despite their suspected endocrine
disrupting properties. In this study, the potential (anti-)androgenic effects of ten conazoles were …