User profiles for Majorie B. M. van Duursen
Majorie van DuursenVrije Universiteit Verified email at vu.nl Cited by 2184 |
Modulation of estrogen synthesis and metabolism by phytoestrogens in vitro and the implications for women's health
MBM Van Duursen - Toxicology Research, 2017 - academic.oup.com
Phytoestrogens are increasingly used as dietary supplements due to their suggested health
promoting properties, but also by women for breast enhancement and relief of menopausal …
promoting properties, but also by women for breast enhancement and relief of menopausal …
[HTML][HTML] Experimental human placental models for studying uptake, transport and toxicity of micro-and nanoplastics
HM Dusza, J van Boxel, MBM van Duursen… - Science of The Total …, 2023 - Elsevier
Micro- and nanoplastics (MNPs) are ubiquitous in the environment and have recently been
found in human lungs, blood and placenta. However, data on the possible effects of MNPs on …
found in human lungs, blood and placenta. However, data on the possible effects of MNPs on …
[HTML][HTML] Safeguarding female reproductive health against endocrine disrupting chemicals—The FREIA project
MBM van Duursen, J Boberg, S Christiansen… - International journal of …, 2020 - mdpi.com
Currently available test methods are not well-suited for the identification of chemicals that
disturb hormonal processes involved in female reproductive development and function. This …
disturb hormonal processes involved in female reproductive development and function. This …
Structural bisphenol analogues differentially target steroidogenesis in murine MA-10 Leydig cells as well as the glucocorticoid receptor
…, TFH Bovee, AH Piersma, MBM van Duursen - Toxicology, 2015 - Elsevier
Although much information on the endocrine activity of bisphenol A (BPA) is available, a proper
human hazard assessment of analogues that are believed to have a less harmful toxicity …
human hazard assessment of analogues that are believed to have a less harmful toxicity …
Endocrine Disruptors Differentially Target ATP-Binding Cassette Transporters in the Blood-Testis Barrier and Affect Leydig Cell Testosterone Secretion In Vitro
…, M van den Berg, MBM van Duursen… - toxicological …, 2013 - academic.oup.com
Endocrine-disrupting chemicals (EDCs) are considered to cause testicular toxicity primarily
via interference with steroid hormone function. Alternatively, EDCs could possibly exert their …
via interference with steroid hormone function. Alternatively, EDCs could possibly exert their …
[HTML][HTML] A new highly specific and robust yeast androgen bioassay for the detection of agonists and antagonists
…, ARM Hamers, MBM van Duursen… - Analytical and …, 2007 - Springer
Public concern about the presence of natural and anthropogenic compounds which affect
human health by modulating normal endocrine functions is continuously growing. Fast and …
human health by modulating normal endocrine functions is continuously growing. Fast and …
Anti-aromatase effect of resveratrol and melatonin on hormonal positive breast cancer cells co-cultured with breast adipose fibroblasts
S Chottanapund, MBM Van Duursen, P Navasumrit… - Toxicology in Vitro, 2014 - Elsevier
Targeting the estrogen pathway has been proven effective in the treatment for estrogen
receptor positive breast cancer. There are currently two common groups of anti-estrogenic …
receptor positive breast cancer. There are currently two common groups of anti-estrogenic …
Genistein induces breast cancer-associated aromatase and stimulates estrogen-dependent tumor cell growth in in vitro breast cancer model
MBM van Duursen, SM Nijmeijer, ES De Morree… - Toxicology, 2011 - Elsevier
In breast cancer, the interaction between estrogen-producing breast adipose fibroblasts (BAFs)
and estrogen-dependent epithelial tumor cells is pivotal. Local estrogen production is …
and estrogen-dependent epithelial tumor cells is pivotal. Local estrogen production is …
Potential health and environmental risks of three-dimensional engineered polymers
Polymer engineering, such as in three-dimensional (3D) printing, is rapidly gaining popularity,
not only in the scientific and medical fields but also in the community in general. However, …
not only in the scientific and medical fields but also in the community in general. However, …
[HTML][HTML] Conazole fungicides inhibit Leydig cell testosterone secretion and androgen receptor activation in vitro
…, AH Piersma, M van den Berg, MBM van Duursen - Toxicology reports, 2014 - Elsevier
Conazole fungicides are widely used in agriculture despite their suspected endocrine
disrupting properties. In this study, the potential (anti-)androgenic effects of ten conazoles were …
disrupting properties. In this study, the potential (anti-)androgenic effects of ten conazoles were …