Glyphosate-based herbicides are toxic and endocrine disruptors in human cell lines

…, C Dumont, N Benachour, E Clair, MC Chagnon… - Toxicology, 2009 - Elsevier
Glyphosate-based herbicides are the most widely used across the world; they are commercialized
in different formulations. Their residues are frequent pollutants in the environment. In …

Chemical compounds and toxicological assessments of drinking water stored in polyethylene terephthalate (PET) bottles: a source of controversy reviewed

C Bach, X Dauchy, MC Chagnon, S Etienne - Water research, 2012 - Elsevier
A declaration of conformity according to European regulation No. 10/2011 is required to
ensure the safety of plastic materials in contact with foodstuffs. This regulation established a …

In-mouth mechanisms leading to flavor release and perception

C Salles, MC Chagnon, G Feron… - Critical reviews in …, 2010 - Taylor & Francis
During eating, foods are submitted to two main oral processes—chewing, including biting and
crushing with teeth, and progressive impregnation by saliva resulting in the formation of a …

Effect of temperature on the release of intentionally and non-intentionally added substances from polyethylene terephthalate (PET) bottles into water: chemical …

…, I Severin, JF Munoz, S Etienne, MC Chagnon - Food Chemistry, 2013 - Elsevier
The purpose of this study was to investigate the impact of temperature on the release of PET-bottle
constituents into water and to assess the potential health hazard using in vitro …

Pharmacokinetics and metabolism of apigenin in female and male rats after a single oral administration

…, JP Basly, R Berges, C Teyssier, MC Chagnon… - Drug Metabolism and …, 2005 - ASPET
The metabolism of apigenin, a weak estrogenic flavonoid phytochemical, was investigated
in the rat. After a single oral administration of radiolabeled apigenin, 51.0% of radioactivity …

Is bisphenol S a safe substitute for bisphenol A in terms of metabolic function? An in vitro study

…, L Peyre, C Costanzo, MC Chagnon… - Toxicology and applied …, 2014 - Elsevier
As bisphenol A (BPA) has been shown to induce adverse effects on human health,
especially through the activation of endocrine pathways, it is about to be withdrawn from the …

Genotoxic and endocrine activities of bis (hydroxyphenyl) methane (bisphenol F) and its derivatives in the HepG2 cell line

…, E Perdu, D Zalko, M Cherkaoui-Malki, MC Chagnon - Toxicology, 2009 - Elsevier
Human can be exposed to bis(hydroxyphenyl)methane (bisphenol F or BPF) and its derivatives
as environment and food’s contaminants. This study was investigated to identify and to …

Evaluation of anti-androgenic activity of di-(2-ethylhexyl) phthalate

…, G Nourdin, JF Régnier, JC Lhuguenot, MC Chagnon - Toxicology, 2005 - Elsevier
DEHP is a widely used platiciser in the manufacture of PVC-based materials. It is known to
disrupt the reproductive tract development in male rats. We have performed the Hershberger …

Use of HepG2 cell line for direct or indirect mutagens screening: comparative investigation between comet and micronucleus assays

…, JC Lhuguenot, AM Le Bon, MC Chagnon - … /Genetic Toxicology and …, 2003 - Elsevier
In the present study, DNA-damage and clastogenic or aneugenic effects of genotoxic compounds
were examined in a metabolically competent human cell line (HepG2 cells) using the …

Salivary protein profiles and sensitivity to the bitter taste of caffeine

…, G Lucchi, P Ducoroy, MC Chagnon… - Chemical …, 2012 - academic.oup.com
The interindividual variation in the sensitivity to bitterness is attributed in part to genetic
polymorphism at the taste receptor level, but other factors, such as saliva composition, might be …