User profiles for Martin Radtke

Martin Radtke

BAM Bundesanstalt für Materialforschung und -prüfung
Verified email at bam.de
Cited by 2849

Artemisone—a highly active antimalarial drug of the artemisinin class

…, B Beckermann, M Gerisch, M Radtke… - Angewandte Chemie …, 2006 - Wiley Online Library
The artemisinins are the most potent and rapidly acting antimalarial drugs. In response to
the global threat of multidrug-resistant malaria, they are now widely used in combination …

Discovery of riociguat (BAY 63‐2521): a potent, oral stimulator of soluble guanylate cyclase for the treatment of pulmonary hypertension

…, A Knorr, D Lang, K Muenter, M Radtke… - ChemMedChem …, 2009 - Wiley Online Library
Direct stimulation of soluble guanylate cyclase (sGC) represents a promising therapeutic
strategy for the treatment of a range of diseases, including the severely disabling pulmonary …

Lack of effect of ketoconazole-mediated CYP3A inhibition on sorafenib clinical pharmacokinetics

…, J Lettieri, F Cihon, M Gallentine, M Radtke… - Cancer chemotherapy …, 2006 - Springer
Sorafenib is a novel, small-molecule anticancer compound that inhibits tumor cell proliferation
by targeting Raf in the Raf/MEK/ERK signalling pathway, and inhibits angiogenesis by …

Synchrotron radiation X‐Ray fluorescence at the LNLS: beamline instrumentation and experiments

CA Pérez, M Radtke, HJ Sánchez… - X‐Ray Spectrometry …, 1999 - Wiley Online Library
The x‐ray fluorescence beamline of the Laboratorio Nacional de Luz Síncrotron (LNLS) is
described. The main optical component of the beamline is a silicon (111) channel‐cut …

Determining Structure‐Activity Relationships in Oxide Derived CuSn Catalysts During CO2 Electroreduction Using X‐Ray Spectroscopy

…, A Guilherme Buzanich, M Radtke… - Advanced Energy …, 2022 - Wiley Online Library
The development of earth‐abundant catalysts for selective electrochemical CO 2 conversion
is a central challenge. CuSn bimetallic catalysts can yield selective CO 2 reduction toward …

Compact pnCCD-based X-ray camera with high spatial and energy resolution: a color X-ray camera

…, M Lang, N Langhoff, A Liebel, M Radtke… - Analytical …, 2011 - ACS Publications
For many applications there is a requirement for nondestructive analytical investigation of the
elemental distribution in a sample. With the improvement of X-ray optics and spectroscopic …

A new pnCCD-based color X-ray camera for fast spatial and energy-resolved measurements

…, M Lang, N Langhoff, A Liebel, M Radtke… - Nuclear Instruments and …, 2011 - Elsevier
We present a new high resolution X-ray imager based on a pnCCD detector and a polycapillary
optics. The properties of the pnCCD like high quantum efficiency, high energy resolution …

Layout and first XRF applications of the BAMline at BESSY II

…, W Görner, BR Müller, M Radtke… - X‐Ray Spectrometry …, 2005 - Wiley Online Library
The first hard x‐ray beamline at BESSY II has been installed by BAM and PTB at a
superconducting 7 T wavelength shifter. The main optical elements of the beamline are a double‐…

[HTML][HTML] Metabolism and pharmacokinetic drug–drug interaction profile of vericiguat, a soluble guanylate cyclase stimulator: results from Preclinical and Phase I …

…, M Gerrits, J Lemmen, W Mueck, M Radtke… - Clinical …, 2020 - Springer
Background Vericiguat is a stimulator of soluble guanylate cyclase currently under investigation
as a first-in-class therapy for worsening chronic heart failure (NCT02861534). Patients …

[HTML][HTML] Deterioration mechanism of alkali-activated materials in sulfuric acid and the influence of Cu: A micro-to-nano structural, elemental and stable isotopic multi …

…, M Bertmer, AG Buzanich, M Radtke… - Cement and concrete …, 2021 - Elsevier
In this study, a multi-proxy approach combining 29 Si, 27 Al and 1 H MAS-NMR, FEG-EPMA,
XANES at the Cu K-edge and XRD analytics with hydrochemical tools such as ICP-OES …