Tissue-specific GATA factors are transcriptional effectors of the small GTPase RhoA
F Charron, G Tsimiklis, M Arcand… - Genes & …, 2001 - genesdev.cshlp.org
Rho-like GTPases play a pivotal role in the orchestration of changes in the actin cytoskeleton
in response to receptor stimulation, and have been implicated in transcriptional activation, …
in response to receptor stimulation, and have been implicated in transcriptional activation, …
Development of homogeneous nonradioactive methyltransferase and demethylase assays targeting histone H3 lysine 4
…, M Caron, L Pedro, M Arcand… - Journal of …, 2012 - journals.sagepub.com
Histone posttranslational modifications are among the epigenetic mechanisms that modulate
chromatin structure and gene transcription. Histone methylation and demethylation are …
chromatin structure and gene transcription. Histone methylation and demethylation are …
Single-Well Monitoring of Protein− Protein Interaction and Phosphorylation− Dephosphorylation Events
M Arcand, P Roby, R Bossé, F Lipari, J Padrós… - Biochemistry, 2010 - ACS Publications
We combined oxygen channeling assays with two distinct chemiluminescent beads to detect
simultaneously protein phosphorylation and interaction events that are usually monitored …
simultaneously protein phosphorylation and interaction events that are usually monitored …
Modulation of CYP1A2 and CYP3A6 catalytic activities by serum from rabbits with a turpentine-induced inflammatory reaction and interleukin 6
O Kourylko, C Fradette, M Arcand… - Drug metabolism and …, 2006 - ASPET
Inflammatory reactions reduce the activity of cytochrome P450 isoforms. The aim of the
study was to determine the mechanisms underlying the decrease in CYP1A2 and CYP3A6 …
study was to determine the mechanisms underlying the decrease in CYP1A2 and CYP3A6 …
[HTML][HTML] Catalytic specificity of human protein tyrosine kinases revealed by Peptide substrate profiling
J Blouin, P Roby, M Arcand, L Beaudet… - Current chemical …, 2011 - ncbi.nlm.nih.gov
Out of the 90 human protein tyrosine kinases, 81 were assayed with short peptides derived
from well-characterized [CDK1 (Tyr15), IRS1 (Tyr983), and JAK1 (Tyr1023)] or generic […
from well-characterized [CDK1 (Tyr15), IRS1 (Tyr983), and JAK1 (Tyr1023)] or generic […
Signal transduction pathways implicated in the decrease in CYP1A1, 1A2 and 3A6 activity produced by serum from rabbits and humans with an inflammatory reaction
…, AM Bleau, D Michaud, O Kourylko, M Arcand… - Biochemical …, 2004 - Elsevier
Incubation of serum from rabbits with a turpentine-induced inflammatory reaction and from
humans with an upper respiratory viral infection with hepatocytes from rabbits with a turpentine…
humans with an upper respiratory viral infection with hepatocytes from rabbits with a turpentine…
Phosphorylation of the MAPKKK Regulator Ste50p in Saccharomyces cerevisiae: a Casein Kinase I Phosphorylation Site Is Required for Proper Mating Function
C Wu, M Arcand, G Jansen, M Zhong, T Iouk… - Eukaryotic …, 2003 - Am Soc Microbiol
The Ste50 protein of Saccharomyces cerevisiae is a regulator of the Ste11p protein kinase.
Ste11p is a member of the MAP3K (or MEKK) family, which is conserved from yeast to …
Ste11p is a member of the MAP3K (or MEKK) family, which is conserved from yeast to …
Characterization of a specific binding site for angiotensin II in chicken liver
…, G Servant, J Pérodin, M Arcand… - Canadian journal of …, 1997 - cdnsciencepub.com
We have characterized a specific binding site for angiotensin II (AngII) in chicken liver
membranes. Pseudo-equilibrium studies at 22 C for 30 min have shown that this binding site …
membranes. Pseudo-equilibrium studies at 22 C for 30 min have shown that this binding site …
Development of homogeneous non-radioactive assays for studying histone 3 methyltransferases and demethylases
…, J Blouin, C Normand, A Labonté, H Plante, M Arcand… - Cancer Research, 2011 - AACR
Post-translational modifications of histones are among the epigenetic mechanisms that can
affect chromatin structure and function. Disruption of epigenetic processes can lead to …
affect chromatin structure and function. Disruption of epigenetic processes can lead to …
High-throughput, homogeneous in cyto assays to monitor histone H3 post-translational modifications
…, A Labonté, JF Michaud, N Rouleau, M Arcand - Cancer Research, 2012 - AACR
Histone proteins are an integral part of DNA packaging into chromatin, a dynamic process
partly regulated by post-translation modification of histone N-terminal tails. Aberrant histone …
partly regulated by post-translation modification of histone N-terminal tails. Aberrant histone …