User profiles for Melissa J. Beck

Melissa J Beck

Associate Professor, Cedarville University
Verified email at cedarville.edu
Cited by 1255

[HTML][HTML] Phenotypic characterization of recessive gene knockout rat models of Parkinson's disease

…, S De Silva, NP Sheth, S Ramboz, MJ Beck… - Neurobiology of …, 2014 - Elsevier
Recessively inherited loss-of-function mutations in the PTEN-induced putative kinase 1(Pink1),
DJ-1 (Park7) and Parkin (Park2) genes are linked to familial cases of early-onset …

[HTML][HTML] Loss of leucine-rich repeat kinase 2 (LRRK2) in rats leads to progressive abnormal phenotypes in peripheral organs

…, KD Dave, MA Frasier, TB Sherer, M Greeley, MJ Beck… - PloS one, 2013 - journals.plos.org
The objective of this study was to evaluate the pathology time course of the LRRK2 knockout
rat model of Parkinson’s disease at 1-, 2-, 4-, 8-, 12-, and 16-months of age. The evaluation …

Developmental neurotoxicity study of dietary bisphenol A in Sprague-Dawley rats

DG Stump, MJ Beck, A Radovsky… - Toxicological …, 2010 - academic.oup.com
This study was conducted to determine the potential of bisphenol A (BPA) to induce functional
and/or morphological effects to the nervous system of F 1 offspring from dietary exposure …

28-Day oral (gavage) toxicity studies of green tea catechins prepared for beverages in rats

…, KS Regan, AE Radovsky, MJ Beck… - Food and Chemical …, 2008 - Elsevier
The beneficial health effects associated with drinking green tea are widely considered to be
due primarily to tea catechins. Heat treatment of marketed green tea beverages for …

[HTML][HTML] Cholinesterase inhibition and toxicokinetics in immature and adult rats after acute or repeated exposures to chlorpyrifos or chlorpyrifos–oxon

…, AW Perala, KA Brzak, MJ Bartels, MJ Beck… - Regulatory Toxicology …, 2012 - Elsevier
The effect of age or dose regimen on cholinesterase inhibition (ChEI) from chlorpyrifos (CPF)
or CPF–oxon (CPFO) was studied in Crl:CD(SD) rats. Rats were exposed to CPF by …

Nonclinical juvenile toxicity testing

MJ Beck, EL Padgett, GA Parker… - Developmental and …, 2016 - taylorfrancis.com
The use of animals to evaluate the potential adverse effects of xenobiotics (environmental
chemicals or therapeutic agents) is required as an essential component of safety and risk …

Safety assessment of heat-sterilized green tea catechin preparation: a 6-month repeat-dose study in rats

…, Y Tamaki, CP Chengelis, MJ Beck… - Food and chemical …, 2009 - Elsevier
Evidence suggests that the purported health benefits associated with green tea consumption
are related to tea catechins. In the present study, potential adverse effects of a standardized …

[HTML][HTML] Dietary administration of paraquat for 13 weeks does not result in a loss of dopaminergic neurons in the substantia nigra of C57BL/6J mice

…, M Butt, JC Wolf, D Zadory, MJ Beck… - Regulatory Toxicology …, 2014 - Elsevier
Several investigations have reported that mice administered paraquat dichloride (PQ·Cl 2 )
by intraperitoneal injection exhibit a loss of dopaminergic neurons in the substantia nigra …

An oral developmental neurotoxicity study of decabromodiphenyl ether (DecaBDE) in rats

JA Biesemeier, MJ Beck, H Silberberg… - … Research Part B …, 2011 - Wiley Online Library
BACKGROUND: Decabromodiphenyl ether (DecaBDE; CASRN 1163‐19‐5) is a flame
retardant used in a variety of manufactured products. A single oral dose of 20.1 mg/kg …

Characterization of the T-dependent antibody response (TDAR) to keyhole limpet hemocyanin (KLH) in the Göttingen minipig

VL Peachee, MJ Smith, MJ Beck… - Journal of …, 2014 - Taylor & Francis
Recently, there has been a renewed interest in the use of the minipig as an alternative to dogs
and non-human primates for conducting toxicological assessments in non-rodent species. …