Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms

…, M Amani, Y Zhao, A Dong, GA Wasney, M Gao… - Molecular and …, 2007 - Elsevier
Parasites from the protozoan phylum Apicomplexa are responsible for diseases, such as
malaria, toxoplasmosis and cryptosporidiosis, all of which have significantly higher rates of …

Pharmacologic profile of the Adnectin BMS-962476, a small protein biologic alternative to PCSK9 antibodies for low-density lipoprotein lowering

…, S Low, K Russo, R DiBella, F Denhez, M Gao… - … of Pharmacology and …, 2014 - ASPET
Proprotein convertase subtilisin kexin-9 (PCSK9) is an important pharmacological target for
decreasing low-density lipoprotein (LDL) in cardiovascular disease, although seemingly …

[HTML][HTML] Comparison of the functional characteristics of the nucleotide binding domains of multidrug resistance protein 1

M Gao, HR Cui, DW Loe, CE Grant, KC Almquist… - Journal of Biological …, 2000 - ASBMB
Multidrug Resistance Protein 1 (MRP1) transports diverse organic anionic conjugates and
confers resistance to cytotoxic xenobiotics. The protein contains two nucleotide binding …

Discovery and preclinical characterization of the cyclopropylindolobenzazepine BMS-791325, a potent allosteric inhibitor of the hepatitis C virus NS5B polymerase

…, RJ Colonno, M Gao, SB Roberts, Q Gao… - Journal of Medicinal …, 2014 - ACS Publications
Described herein are structure–activity relationship studies that resulted in the optimization
of the activity of members of a class of cyclopropyl-fused indolobenzazepine HCV NS5B …

[HTML][HTML] Role of carboxylate residues adjacent to the conserved core Walker B motifs in the catalytic cycle of multidrug resistance protein 1 (ABCC1)

LF Payen, M Gao, CJ Westlake, SPC Cole… - Journal of Biological …, 2003 - ASBMB
MRP1 belongs to subfamily "C" of the ABC transporter superfamily. The nucleotide-binding
domains (NBDs) of the C family members are relatively divergent compared with many ABC …

[HTML][HTML] Multidrug resistance protein: identification of regions required for active transport of leukotriene C4

M Gao, M Yamazaki, DW Loe, CJ Westlake… - Journal of Biological …, 1998 - ASBMB
Multidrug resistance protein (MRP) is a broad specificity, primary active transporter of organic
anion conjugates that confers a multidrug resistance phenotype when transfected into drug…

Crystal structure of microtubule affinity-regulating kinase 4 catalytic domain in complex with a pyrazolopyrimidine inhibitor

JS Sack, M Gao, SE Kiefer, JE Myers… - … Section F: Structural …, 2016 - scripts.iucr.org
Microtubule-associated protein/microtubule affinity-regulating kinase 4 (MARK4) is a serine/threonine
kinase involved in the phosphorylation of MAP proteins that regulate microtubule …

One-pot hydrothermal in situ growth of In4SnS8@ MoS2@ CNTs as efficient Pt-free counter electrodes for dye-sensitized solar cells

M Gao, Z Shen, G Yue, C Dong, J Wu, Y Gao… - Journal of Alloys and …, 2023 - Elsevier
Developing a synthesis method for large-scale preparation of efficient and economical non
noble metal counter electrode (CE) electrocatalytic materials with good catalytic ability and …

Structural determinants of substrate specificity differences between human multidrug resistance protein (MRP) 1 (ABCC1) and MRP3 (ABCC3)

CE Grant, M Gao, MK DeGorter, SPC Cole… - Drug metabolism and …, 2008 - ASPET
Multidrug resistance proteins (MRPs) are members of the “C” branch of the ATP-binding
cassette transporter superfamily. Human MRP1 transports a wide range of natural product drugs …

Tungsten Phosphide Microsheets In‐Situ Grown on Carbon Fiber as Counter Electrode Catalyst for Efficient Dye‐Sensitized Solar Cells

M Gao, Z Shen, X Liu, G Yue, Y Gao… - Advanced Materials …, 2023 - Wiley Online Library
The development of low‐cost, green, and pollution‐free counter electrode materials with
high catalytic activity plays a critical role in improving the photovoltaic performance of dye‐…