Selective involvement of cytochrome P450 2D subfamily in in vivo 4-hydroxylation of amphetamine in rat

MYL Law, MH Slawson, DE Moody - Drug metabolism and disposition, 2000 - ASPET
The cytochrome P450 (P450) 2D subfamily catalyzes ring hydroxylation of amphetamines.
We tested the hypothesis that P450 2D is selectively involved in amphetamine 4-hydroxylation…

Lipids in the pathogenesis of ichthyosis: topical cholesterol sulfate-induced scaling in hairless mice

…, ML Williams, EH Epstein Jr, MYL Law… - Journal of investigative …, 1984 - Elsevier
Although several abnormalities of lipid metabolism have been associated with abnormal
cornification in humans, evidence that these lipids directly provoke abnormal scale is lacking. …

Diazacholesterol-induced ichthyosis in the hairless mouse: Assay for comparative potency of topical retinoids

JC Chung, MYL Law, ST Elliott… - Archives of …, 1984 - jamanetwork.com
• Although the new synthetic retinoids are effective when administered systemically, they
have not been shown to be effective as topical agents. We compared the topical activity of six …

Urinary excretion of 4-hydroxyamphetamine and amphetamine in male and female Sprague-Dawley and Dark Agouti rats following multiple doses of amphetamine

MYL Law, DE Moody - Toxicology letters, 2000 - Elsevier
Previous studies have demonstrated that the cytochrome P450 2D subfamily is involved in
the 4-hydroxylation of amphetamine in the rat. These studies followed urinary levels of 4-…

Arecoline-induced skin inflammation: irritant or allergic dermatitis?

MYL Law, LK Pershing, LK Roberts - International journal of pharmaceutics, 1992 - Elsevier
A severe skin inflammatory reaction halted the development of a transdermal device to
systemically deliver arecoline, a cholinergic agonist, for use in the management of a human …

Neighborhood design and active aging

YL Michael, MK Green, SA Farquhar - Health & place, 2006 - Elsevier
… Pedestrian Summit providing citizens and policy makers an opportunity to discuss specific
actions to encourage active neighborhoods, including enforcement of pedestrian safety laws

[HTML][HTML] The impact of longitudinal substance use patterns on the risk of opioid agonist therapy discontinuation: A repeated measures latent class analysis

Z Cui, M Karamouzian, M Law, K Hayashi… - International Journal of …, 2023 - Springer
Polysubstance use is prevalent among individuals on opioid agonist treatment (OAT), yet
past studies have focused primarily on distinct substances and their association with OAT …

The conserved histone deacetylase Rpd3 and its DNA binding subunit Ume6 control dynamic transcript architecture during mitotic growth and meiotic development

A Lardenois, I Stuparevic, Y Liu, MJ Law… - Nucleic acids …, 2015 - academic.oup.com
It was recently reported that the sizes of many mRNAs change when budding yeast cells exit
mitosis and enter the meiotic differentiation pathway. These differences were attributed to …

Developing a reliable senior walking environmental assessment tool

GO Cunningham, YL Michael, SA Farquhar… - American journal of …, 2005 - Elsevier
BACKGROUND: Research of the effects of the built environment on physical activity often
excludes certain segments of the population. The senior population, one segment perhaps …

Green maintainability design criteria for nanostructured titanium dioxide (TiO2) façade coatings

MYL Chew, S Conejos, JSL Law - International Journal of Building …, 2017 - emerald.com
Purpose Nanostructured titanium dioxide (TiO 2 ) coatings can potentially address the
current surge in façade cleaning cost, maintenance and labour problems. The purpose of this …