The mechanism underlying subcutaneous absorption of macromolecules and factors that
can influence this process were studied in rats using PEGylated erythropoietins (EPOs) as …

Background: Ertapenem is a carbapenem antibiotic with broad spectrum activity and a
pharmacokinetic profile that favors once-daily administration in adults. Objectives: This …

Two stability challenges were encountered during development of an urine assay for a
proliferator-activated receptor (PPAR) agonist, I (2-{[5,7-dipropyl-3-(trifluoromethyl)-1,2-…

I, 2-{[5,7-dipropyl-3-(trifluoromethyl)-1,2-benzisoxazol-6-yl]oxy}-2-methyl propionic acid is
an α peroxisome proliferator-activated receptor (PPAR) agonist with some γ activity being …

We describe how modeling and simulation guided program decisions following a randomized
placebo-controlled single-rising oral dose first-in-man trial of compound A where an …

Raising children is no easy task. No matter the child, no matter the situation, every parent
longs for obedience from their offspring. God isnt overbearing when He deals with us, and His …

… DEDICATION This dissertation is dedicated to my parents, Jim and Nancy Phillips, without
whom this would not have been possible; to Chris and Michelle Groff, who have been …

The chemoattractant receptor-homologous molecule expressed on T-helper type 2 cells (CRTH2)
is a G protein-coupled receptor that has been reported to modulate inflammatory …

Infection with Veronaea botryosa can result in rare cutaneous or disseminated, granulomatous
to pyogranulomatous phaeohyphomycosis in humans, although disease due to the …

The study of crime has focused primarily on why particular people commit crime or why
specific communities have higher crime levels than others. In The Criminology of Place, David …