Crystal structure analyses of reduced (CuI) poplar plastocyanin at six pH values
JM Guss, PR Harrowell, M Murata, VA Norris… - Journal of molecular …, 1986 - Elsevier
The structure of poplar plastocyanin in the reduced (Cu I ) state has been determined and
refined, using counter data recorded from crystals at pH 3.8, 4.4, 5.1, 5.9, 7.0 and 7.8 (…
refined, using counter data recorded from crystals at pH 3.8, 4.4, 5.1, 5.9, 7.0 and 7.8 (…
Novel epoxysuccinyl peptides selective inhibitors of cathepsin B, in vitro
M Murata, S Miyashita, C Yokoo, M Tamai, K Hanada… - FEBS letters, 1991 - Elsevier
A series of new epoxysuccinyl peptides were designed and synthesized to develop a
specific inhibitor of cathepsin B. Of these compounds, N-(L-3-trans-ethoxycarbonyloxirane-2-…
specific inhibitor of cathepsin B. Of these compounds, N-(L-3-trans-ethoxycarbonyloxirane-2-…
CA074 methyl ester: a proinhibitor for intracellular cathepsin B
DJ Buttle, M Murata, CG Knight, AJ Barrett - Archives of biochemistry and …, 1992 - Elsevier
The specificity of compound CA074 [N-(l-3-trans-propylcarbamoyloxirane-2-carbonyl)-l-isoleucyl-l-proline]
for the inactivation of cathepsin B was quantified in in vitro measurements …
for the inactivation of cathepsin B was quantified in in vitro measurements …
Novel epoxysuccinyl peptides A selective inhibitor of cathepsin B, in vivo
T Towatari, T Nikawa, M Murata, C Yokoo… - FEBS …, 1991 - Wiley Online Library
New derivatives of E‐64 (compound CA‐030 and CA‐074) were tested in vitro and in vivo
for selective inhibition of cathepsin B. They exhibited 10000–30000 times greater inhibitory …
for selective inhibition of cathepsin B. They exhibited 10000–30000 times greater inhibitory …
Phase determination by multiple-wavelength x-ray diffraction: crystal structure of a basic" blue" copper protein from cucumbers
…, EA Merritt, RP Phizackerley, B Hedman, M Murata… - Science, 1988 - science.org
A novel x-ray diffraction technique, multiple-wavelength anomalous dispersion (MAD) phasing,
has been applied to the de novo determination of an unknown protein structure, that of …
has been applied to the de novo determination of an unknown protein structure, that of …
Inhibition of bone resrption by selctive inactivators of cysteine proteinases
…, DJ Buttle, SJ Jones, A Boyde, M Murata… - Journal of cellular …, 1994 - Wiley Online Library
Incativators of cystein proteinases (CPs) were tested as inhibitors of bone resorption in vitro
and in vivo. The following four CP inactivators were tested: Ep453, the membrane‐permeant …
and in vivo. The following four CP inactivators were tested: Ep453, the membrane‐permeant …
Stimulation of glucose uptake in muscle cells by prolonged treatment with scriptide, a histone deacetylase inhibitor
H Takigawa-Imamura, T Sekine, M Murata… - Bioscience …, 2003 - Taylor & Francis
Glucose incorporation is regulated mainly by GLUT4 in skeletal muscles. Here we report
that treatment of L6 myotubes with scriptide, a hydroxamic acid-based histone deacetylase (…
that treatment of L6 myotubes with scriptide, a hydroxamic acid-based histone deacetylase (…
Inhibition of cartilage proteoglycan release by a specific inactivator of cathepsin b and an inhibitor of matrix metalloproteinases. evidence for two converging pathways …
…, MZ Ilic, J Saklatvala, M Murata… - Arthritis & …, 1993 - Wiley Online Library
Objective. To investigate mechanisms of cartilage matrix destruction by a study of the effects
of a specific inactivator of cathepsin B and an inhibitor of several matrix metalloproteinases (…
of a specific inactivator of cathepsin B and an inhibitor of several matrix metalloproteinases (…
Binding mode of CA074, a specific irreversible inhibitor, to bovine cathepsin B as determined by X-ray crystal analysis of the complex
…, T Ishida, T Fujii, Y Hata, M Murata… - The journal of …, 1997 - academic.oup.com
The binding mode of CA074 [N-(L-3-trans-propylcarbamoyl-oxirane-2-carbonyl)-L-isoleucyl-L-proline],
a specific irreversible inhibitor, to bovine spleen cathepsin B was elucidated by X-…
a specific irreversible inhibitor, to bovine spleen cathepsin B was elucidated by X-…
Substrate specificity of bovine cathepsin B and its inhibition by CA074, based on crystal structure refinement of the complex
A Yamamoto, K Tomoo, T Hara, M Murata… - The journal of …, 2000 - academic.oup.com
The crystal structure of the bovine spleen cathepsin B (BSCB)-CA074 complex was refined
to R = 0.152 using X-ray diffraction data up to 2.18 A resolution. BSCB is characterized by an …
to R = 0.152 using X-ray diffraction data up to 2.18 A resolution. BSCB is characterized by an …