Degradation of ginsenosides in humans after oral administration
MA Tawab, U Bahr, M Karas, M Wurglics… - Drug metabolism and …, 2003 - ASPET
Even though the degradation of ginsenosides has been thoroughly studied in animals and
in vitro using acids, enzymes, and intestinal bacteria, knowledge concerning the systemic …
in vitro using acids, enzymes, and intestinal bacteria, knowledge concerning the systemic …
Boswellia serrata: An Overall Assessment of In Vitro, Preclinical, Pharmacokinetic and Clinical Data
M Abdel-Tawab, O Werz… - Clinical pharmacokinetics, 2011 - Springer
Non-steroidal anti-inflammatory drug (NSAID) intake is associated with high prevalence of
gastrointestinal or cardiovascular adverse effects. All efforts to develop NSAIDs that spare the …
gastrointestinal or cardiovascular adverse effects. All efforts to develop NSAIDs that spare the …
Carnosic acid and carnosol, phenolic diterpene compounds of the labiate herbs rosemary and sage, are activators of the human peroxisome proliferator-activated …
…, A Bock, T Dingermann, M Abdel-Tawab… - Planta …, 2006 - thieme-connect.com
Peroxisome proliferator-activated receptor gamma (PPARγ) is a ligand activated transcription
factor, belonging to the metazoan family of nuclear hormone receptors. Activation of …
factor, belonging to the metazoan family of nuclear hormone receptors. Activation of …
[HTML][HTML] Best Practice in the chemical characterisation of extracts used in pharmacological and toxicological research—The ConPhyMP—Guidelines12
M Heinrich, B Jalil, M Abdel-Tawab… - Frontiers in …, 2022 - frontiersin.org
Background: Research on medicinal plants and extracts derived from them differs from studies
performed with single compounds. Extracts obtained from plants, algae, fungi, lichens or …
performed with single compounds. Extracts obtained from plants, algae, fungi, lichens or …
Boswellia serrata acts on cerebral edema in patients irradiated for brain tumors: A prospective, randomized, placebo‐controlled, double‐blind pilot trial
…, M Treier, SJ Wehrle, G Becker, M Abdel‐Tawab… - Cancer, 2011 - Wiley Online Library
BACKGROUND: Patients irradiated for brain tumors often suffer from cerebral edema and
are usually treated with dexamethasone, which has various side effects. To investigate the …
are usually treated with dexamethasone, which has various side effects. To investigate the …
Metabolism of boswellic acids in vitro and in vivo
…, M Karas, M Schubert-Zsilavecz, M Abdel-Tawab - Drug metabolism and …, 2008 - ASPET
Boswellia serrata resin dry extract is among the few herbal remedies designated with an
orphan drug status for the treatment of peritumoral brain edema. In addition, boswellic acids (…
orphan drug status for the treatment of peritumoral brain edema. In addition, boswellic acids (…
[HTML][HTML] Enhanced absorption of boswellic acids by a lecithin delivery form (Phytosome®) of Boswellia extract
…, G Appendino, M Schubert-Zsilavecz, M Abdel-Tawab - Fitoterapia, 2013 - Elsevier
The anti-inflammatory potential of Boswellia serrata gum resin extracts has been demonstrated
in vitro and in animal studies as well as in pilot clinical trials. However, pharmacokinetic …
in vitro and in animal studies as well as in pilot clinical trials. However, pharmacokinetic …
Absorption, pharmacokinetics, and safety of triclosan after dermal administration
…, B Bastian, M Abdel-Tawab… - Antimicrobial agents …, 2010 - Am Soc Microbiol
We evaluated the pharmacokinetics and safety of the antimicrobial agent triclosan after
dermal application of a 2% triclosan-containing cream to six volunteers. Percutaneous …
dermal application of a 2% triclosan-containing cream to six volunteers. Percutaneous …
[HTML][HTML] Extracting and analyzing pyrrolizidine alkaloids in medicinal plants: A review
T Kopp, M Abdel-Tawab, B Mizaikoff - Toxins, 2020 - mdpi.com
Pyrrolizidine alkaloids (PAs) are distributed in plant families of Asteraceae, Boraginaceae,
and Fabaceae and serve in the chemical defense mechanism against herbivores. However, …
and Fabaceae and serve in the chemical defense mechanism against herbivores. However, …
In vitro metabolism, permeation, and brain availability of six major boswellic acids from Boswellia serrata gum resins
…, O Werz, M Schubert-Zsilavecz, M Abdel-Tawab - Fitoterapia, 2013 - Elsevier
Boswellia serrata gum resin extracts (BSE) revealed potent anti-inflammatory actions in
preclinical and clinical studies. In 2002 BSE was assigned an orphan drug status by the …
preclinical and clinical studies. In 2002 BSE was assigned an orphan drug status by the …