[HTML][HTML] The lung microbiome during health and disease

K Yagi, GB Huffnagle, NW Lukacs, N Asai - International Journal of …, 2021 - mdpi.com
Healthy human lungs have traditionally been considered to be a sterile organ. However,
culture-independent molecular techniques have reported that large numbers of microbes …

Relapsed small cell lung cancer: treatment options and latest developments

N Asai, Y Ohkuni, N Kaneko… - … advances in medical …, 2014 - journals.sagepub.com
According to recent analyses, there was a modest yet significant improvement in median
survival time and 5-year survival rate of limited stage small cell lung cancer (SCLC) in North

Characterization of a multicomponent receptor for GDNF

…, MW Moore, A Buj-Bello, AM Davies, N Asai… - Nature, 1996 - nature.com
… Sense and antisense probes were derived from the N-terminal region of GDNFR-o using
T7 … in PIPLC-treated Neuro-2a and SK-N-SH cells when GDNF was added together with a …

The RET proto‐oncogene: A molecular therapeutic target in thyroid cancer

Y Kodama, N Asai, K Kawai, M Jijiwa… - Cancer …, 2005 - Wiley Online Library
The RET proto‐oncogene is responsible for the development of several human inherited
and non‐inherited diseases. Germline point mutations were identified in multiple endocrine …

[PDF][PDF] Akt/PKB regulates actin organization and cell motility via Girdin/APE

A Enomoto, H Murakami, N Asai, N Morone… - Developmental cell, 2005 - cell.com
… To test the specificity of the effect of the Girdin knockdown, we also introduced the Girdin
siRNA into another cell line, SK-N-MC neuroblastoma cells, which stably express the RET …

Mechanism of Activation of the ret Proto-oncogene by Multiple Endocrine Neoplasia 2A Mutations

N Asai, T Iwashita, M Matsuyama… - Molecular and cellular …, 1995 - Taylor & Francis
… After lyophilization, the samples were subjected to acid hydrolysis in 50 l of 6 N HCl for 2
h at 110C. Then they were suspended in 1 ml of distilled water and lyophilized three times. …

[HTML][HTML] A GPI-linked protein that interacts with Ret to form a candidate neurturin receptor

…, B Devaux, K Poulsen, M Armanini, C Nozaki, N Asai… - Nature, 1997 - nature.com
… Naoya Asai … Sense and antisense probes were derived for the N-terminal regions of
NTNR-α or GDNFR-α using T7 polymerase. … Naoya Asai

Meflin-positive cancer-associated fibroblasts inhibit pancreatic carcinogenesis

…, T Iida, N Asai, A Masamune, A Hara, N Esaki… - Cancer research, 2019 - AACR
… When we investigated Meflin expression in surgically resected human PDAC tissues (N =
71), we found that the frequency of Meflin + CAFs varies between patients with PDAC (Fig. 3A; …

Regulation of VEGF-mediated angiogenesis by the Akt/PKB substrate Girdin

T Kitamura, N Asai, A Enomoto, K Maeda, T Kato… - Nature cell …, 2008 - nature.com
The serine/threonine protein kinase Akt is involved in a variety of cellular processes including
cell proliferation, survival, metabolism and gene expression. It is essential in vascular …

[PDF][PDF] Ret-dependent cell rearrangements in the Wolffian duct epithelium initiate ureteric bud morphogenesis

…, JD Licht, N Asai, M Takahashi, N Ohgami… - Developmental cell, 2009 - cell.com
While the genetic control of renal branching morphogenesis has been extensively described,
the cellular basis of this process remains obscure. GDNF/RET signaling is required for …