(1S)-1,5-Anhydro-1-[5-(4-ethoxybenzyl)-2-methoxy-4-methylphenyl]-1-thio-d-glucitol (TS-071) is a Potent, Selective Sodium-Dependent Glucose Cotransporter 2 …
…, Y Fukasawa, I Iida, N Hagima… - Journal of medicinal …, 2010 - ACS Publications
… For example, 5′-thio-N-acetyllactosamine is 200 times more resistant to digestion by β-galactosidase,
(39) and methyl α-5′-thiomaltoside is not hydrolyzed at all by glucoamylase …
(39) and methyl α-5′-thiomaltoside is not hydrolyzed at all by glucoamylase …
Involvement of organic cation transporters in the clearance and milk secretion of thiamine in mice
…, N Ito, X Zhang, K Hachiuma, N Hagima… - Pharmaceutical …, 2015 - Springer
… Each point represents the mean value and SEM (n = 4 or 5). * P < 0.05; ** P < 0.01 versus
Oct1/2(+/+). (b) The plasma concentrations of thiamine-d 3 were determined in control (open …
Oct1/2(+/+). (b) The plasma concentrations of thiamine-d 3 were determined in control (open …
Deuterium-Resistant Algal Cell Line for D Labeling of Heterotrophs Expresses Enhanced Level of Hsp60 in D2O Medium
…, N Hagima, T Kishido, S Okada, N Oku - Applied and …, 2005 - Am Soc Microbiol
Fully deuterated components from autotrophic cell lysate are useful materials for labeling of
heterotrophs with deuterium. To facilitate the faster production of deuterated algal lysate, we …
heterotrophs with deuterium. To facilitate the faster production of deuterated algal lysate, we …
Acrylic IOL implantation with the Monarch II injector
…, I Dragan, G Barlea, L Balan, N Hagima - Oftalmologia …, 2003 - europepmc.org
Methods Retrospective study which included 135 eyes with cataract who underwent cataract
surgery between March 2002-August 2003. The surgical intervention consisted of lens …
surgery between March 2002-August 2003. The surgical intervention consisted of lens …
Differences in Cytochrome P450 Forms Involved in the Metabolism ofN, N-Dipropyl-2-[4-methoxy-3-(2-phenylethoxy) phenyl] ethylamine monohydrochloride (NE-100) …
T Yamamoto, N Hagima, M Nakamura, Y Kohno… - Drug metabolism and …, 2003 - ASPET
N,N-Dipropyl-2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethylamine monohydrochloride (NE-100)
has been developed to treat subjects with schizophrenia. This drug is mainly excreted in …
has been developed to treat subjects with schizophrenia. This drug is mainly excreted in …
Growth Delay and Intracellular Changes in Chlorella ellipsoidea C-27 as a Result of Deuteration
K Unno, I Ando, N Hagima, S Yokogaki… - Plant and cell …, 1992 - academic.oup.com
The effects of deuterium (D) on Chlorella ellipsoidea C-27 were investigated. Cells grown in
a medium prepared with deuterium oxide (D 2 O) showed pronounced delays in cell growth …
a medium prepared with deuterium oxide (D 2 O) showed pronounced delays in cell growth …
Prediction of differences in in vivo oral clearance of N,N-dipropyl-2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethylamine monohydrochloride (NE-100) between extensive and …
T Yamamoto, N Hagima, M Nakamura, Y Kohno… - Xenobiotica, 2004 - Taylor & Francis
It has previously been reported that N,N-dipropyl-2-[4-methoxy-3-(2-phenylethoxy)phenyl]-ethylamine
monohydrochloride (NE-100) was predominantly metabolized by cytochrome …
monohydrochloride (NE-100) was predominantly metabolized by cytochrome …
Metabolism of N, N-dipropyl-2-[4-methoxy-3-(2-phenyl-ethoxy)-phenyl]-ethyl-amine-monohydrochloride (NE-100), a novel sigma ligand: contribution of cytochrome …
T Yamamoto, N Hagima, M Fukasawa… - Drug metabolism and …, 2003 - Elsevier
In the present study, human cytochrome P450 (CYP) forms involved in producing the
primary metabolites of NE-100 were identified. Major metabolites of NE-100 in human liver …
primary metabolites of NE-100 were identified. Major metabolites of NE-100 in human liver …
Overview of CSR codes
…, T Agoh, M Dohlus, L Giannessi, R Hajima… - Nuclear Instruments and …, 2006 - Elsevier
… Hajima (Section 5) has a simple analytical model to estimate the emittance growth due to …
by N m number of macroparticles, where each macroparticle has charge q m = Q / N m and rms …
by N m number of macroparticles, where each macroparticle has charge q m = Q / N m and rms …
Nondestructive assay of plutonium and minor actinide in spent fuel using nuclear resonance fluorescence with laser Compton scattering γ-rays
…, N Kikuzawa, R Hajima, T Shizuma, N Nishimori… - Nuclear Instruments and …, 2010 - Elsevier
… In fact, we measured two isotopes of 12 C and 14 N in a chemical compound, melamine (C
3 H 6 N 6 ), through a 15-mm thick iron plate and a 4-mm thick lead plate at AIST [20]. This …
3 H 6 N 6 ), through a 15-mm thick iron plate and a 4-mm thick lead plate at AIST [20]. This …