Cytochrome P450s are oxidative metabolic enzymes that play critical roles in the biotransformation
of endogenous compounds and xenobiotics. The expression and activity of P450 …

The transition from replication to non-replication underlies much of Mycobacterium tuberculosis
(Mtb) pathogenesis, as non- or slowly replicating Mtb are responsible for persistence …

Commensal microorganisms in the mammalian gut play important roles in host health and
physiology, but a central challenge remains in achieving a detailed mechanistic …

… Author links open overlay panel Natalie C Sadler , Aaron T Wright … The first study evaluated
a transition in carbon availability, from C-limited to C-starved then to C-replenished, with in …

Nitrosomonas europaea is an aerobic nitrifying bacterium that oxidizes ammonia (NH 3 ) to
nitrite (NO 2 − ) through the sequential activities of ammonia monooxygenase (AMO) and …

Cytochrome P450 monooxygenase (P450) enzymes metabolize critical endogenous chemicals
and oxidize nearly all xenobiotics. Dysregulated P450 activities lead to altered capacity …

Glutathione S-transferases (GSTs) comprise a diverse family of phase II drug metabolizing
enzymes whose shared function is the conjugation of reduced glutathione (GSH) to endo- …

While deprivation of dietary fiber has been associated with adverse health outcomes,
investigations concerning the effect of dietary fiber on the gut microbiome have been largely limited …

Microbial communities organize into spatial patterns that are largely governed by interspecies
interactions. This phenomenon is an important metric for understanding community …

A multimodal activity‐based probe for targeting acidic organelles was developed to
measure subcellular native enzymatic activity in cells by fluorescence microscopy and mass …