User profiles for Nicolas Picard

Nicolas Picard

- Verified email at gip-ecofor.org - Cited by 7909

Nicolas Picard, PharmD, PhD

- Verified email at unilim.fr - Cited by 2951

Positive biodiversity-productivity relationship predominant in global forests

J Liang, TW Crowther, N Picard, S Wiser, M Zhou… - Science, 2016 - science.org
INTRODUCTION The biodiversity-productivity relationship (BPR; the effect of biodiversity on
ecosystem productivity) is foundational to our understanding of the global extinction crisis …

[HTML][HTML] Spatial validation reveals poor predictive performance of large-scale ecological mapping models

…, M Réjou-Méchain, N Barbier, N Picard… - Nature …, 2020 - nature.com
Mapping aboveground forest biomass is central for assessing the global carbon balance.
However, current large-scale maps show strong disparities, despite good validation statistics of …

Therapeutic drug monitoring of tacrolimus-personalized therapy: second consensus report

…, O Noceti, T Pawinski, N Picard… - Therapeutic drug …, 2019 - journals.lww.com
Ten years ago, a consensus report on the optimization of tacrolimus was published in this
journal. In 2017, the Immunosuppressive Drugs Scientific Committee of the International …

Climatic controls of decomposition drive the global biogeography of forest-tree symbioses

…, GJ Nabuurs, S De-Miguel, M Zhou, N Picard… - Nature, 2019 - nature.com
The identity of the dominant root-associated microbial symbionts in a forest determines the
ability of trees to access limiting nutrients from atmospheric or soil pools 1 , 2 , sequester …

The extent of forest in dryland biomes

…, D Mollicone, R Moore, C Patriarca, N Picard… - Science, 2017 - science.org
Dryland biomes cover two-fifths of Earth’s land surface, but their forest area is poorly known.
Here, we report an estimate of global forest extent in dryland biomes, based on analyzing …

The number of tree species on Earth

…, S Pfautsch, OL Phillips, N Picard… - Proceedings of the …, 2022 - National Acad Sciences
One of the most fundamental questions in ecology is how many species inhabit the Earth.
However, due to massive logistical and financial challenges and taxonomic difficulties …

Is inappropriate medication use a major cause of adverse drug reactions in the elderly?

…, JP Charmes, Y Nouaille, N Picard… - British journal of …, 2007 - Wiley Online Library
What is already known about this subject • Several studies have shown that inappropriate
medications induce adverse health outcomes in the elderly. • The hypothesis of Beers et al. …

[HTML][HTML] Tubular overexpression of transforming growth factor-β1 induces autophagy and fibrosis but not mesenchymal transition of renal epithelial cells

R Koesters, B Kaissling, M LeHir, N Picard… - The American journal of …, 2010 - Elsevier
We recently showed in a tetracycline-controlled transgenic mouse model that overexpression
of transforming growth factor (TGF)-β1 in renal tubules induces widespread peritubular …

Identification of the UDP-glucuronosyltransferase isoforms involved in mycophenolic acid phase II metabolism

N Picard, D Ratanasavanh, A Prémaud… - Drug metabolism and …, 2005 - ASPET
… Pooled human kidney and intestinal microsomes were prepared as previously described
(Picard et al., 2004) from normal kidney (n = 4) and ileal (n = 4) tissues adjoining tumor tissues …

[HTML][HTML] The absence of intrarenal ACE protects against hypertension

…, DM Seth, S Fuchs, D Eladari, N Picard… - The Journal of …, 2013 - Am Soc Clin Investig
Activation of the intrarenal renin-angiotensin system (RAS) can elicit hypertension independently
from the systemic RAS. However, the precise mechanisms by which intrarenal Ang II …