Positive biodiversity-productivity relationship predominant in global forests
INTRODUCTION The biodiversity-productivity relationship (BPR; the effect of biodiversity on
ecosystem productivity) is foundational to our understanding of the global extinction crisis …
ecosystem productivity) is foundational to our understanding of the global extinction crisis …
[HTML][HTML] Spatial validation reveals poor predictive performance of large-scale ecological mapping models
Mapping aboveground forest biomass is central for assessing the global carbon balance.
However, current large-scale maps show strong disparities, despite good validation statistics of …
However, current large-scale maps show strong disparities, despite good validation statistics of …
Therapeutic drug monitoring of tacrolimus-personalized therapy: second consensus report
…, O Noceti, T Pawinski, N Picard… - Therapeutic drug …, 2019 - journals.lww.com
Ten years ago, a consensus report on the optimization of tacrolimus was published in this
journal. In 2017, the Immunosuppressive Drugs Scientific Committee of the International …
journal. In 2017, the Immunosuppressive Drugs Scientific Committee of the International …
Climatic controls of decomposition drive the global biogeography of forest-tree symbioses
The identity of the dominant root-associated microbial symbionts in a forest determines the
ability of trees to access limiting nutrients from atmospheric or soil pools 1 , 2 , sequester …
ability of trees to access limiting nutrients from atmospheric or soil pools 1 , 2 , sequester …
The extent of forest in dryland biomes
Dryland biomes cover two-fifths of Earth’s land surface, but their forest area is poorly known.
Here, we report an estimate of global forest extent in dryland biomes, based on analyzing …
Here, we report an estimate of global forest extent in dryland biomes, based on analyzing …
The number of tree species on Earth
One of the most fundamental questions in ecology is how many species inhabit the Earth.
However, due to massive logistical and financial challenges and taxonomic difficulties …
However, due to massive logistical and financial challenges and taxonomic difficulties …
Is inappropriate medication use a major cause of adverse drug reactions in the elderly?
…, JP Charmes, Y Nouaille, N Picard… - British journal of …, 2007 - Wiley Online Library
What is already known about this subject • Several studies have shown that inappropriate
medications induce adverse health outcomes in the elderly. • The hypothesis of Beers et al. …
medications induce adverse health outcomes in the elderly. • The hypothesis of Beers et al. …
[HTML][HTML] Tubular overexpression of transforming growth factor-β1 induces autophagy and fibrosis but not mesenchymal transition of renal epithelial cells
R Koesters, B Kaissling, M LeHir, N Picard… - The American journal of …, 2010 - Elsevier
We recently showed in a tetracycline-controlled transgenic mouse model that overexpression
of transforming growth factor (TGF)-β1 in renal tubules induces widespread peritubular …
of transforming growth factor (TGF)-β1 in renal tubules induces widespread peritubular …
Identification of the UDP-glucuronosyltransferase isoforms involved in mycophenolic acid phase II metabolism
N Picard, D Ratanasavanh, A Prémaud… - Drug metabolism and …, 2005 - ASPET
… Pooled human kidney and intestinal microsomes were prepared as previously described
(Picard et al., 2004) from normal kidney (n = 4) and ileal (n = 4) tissues adjoining tumor tissues …
(Picard et al., 2004) from normal kidney (n = 4) and ileal (n = 4) tissues adjoining tumor tissues …
[HTML][HTML] The absence of intrarenal ACE protects against hypertension
…, DM Seth, S Fuchs, D Eladari, N Picard… - The Journal of …, 2013 - Am Soc Clin Investig
Activation of the intrarenal renin-angiotensin system (RAS) can elicit hypertension independently
from the systemic RAS. However, the precise mechanisms by which intrarenal Ang II …
from the systemic RAS. However, the precise mechanisms by which intrarenal Ang II …