User profiles for Ola Dale
 | Ola DaleProfesser Emeritus, Anesthesia/Clinical Pharmacology Verified email at ntnu.no Cited by 8847 |
Use of opioid analgesics in the treatment of cancer pain: evidence-based recommendations from the EAPC
Here we provide the updated version of the guidelines of the European Association for
Palliative Care (EAPC) on the use of opioids for the treatment of cancer pain. The update was …
Palliative Care (EAPC) on the use of opioids for the treatment of cancer pain. The update was …
The Val158Met polymorphism of the human catechol-O-methyltransferase (COMT) gene may influence morphine requirements in cancer pain patients
Catechol-O-methyltransferase (COMT) inactivates dopamine, epinephrine and norepinephrine
in the nervous system. A common functional polymorphism (Val158Met) leads to a three- …
in the nervous system. A common functional polymorphism (Val158Met) leads to a three- …
Does intraoperative ketamine attenuate inflammatory reactivity following surgery? A systematic review and meta-analysis
BACKGROUND: Reports regarding the ability of the anesthetic drug ketamine to attenuate
the inflammatory response to surgery are conflicting. In this systematic review we examined …
the inflammatory response to surgery are conflicting. In this systematic review we examined …
Associations between recreational exercise and chronic pain in the general population: evidence from the HUNT 3 study
…, P Romundstad, PC Borchgrevink, S Kaasa, O Dale - PAIN®, 2011 - Elsevier
The evidence for an association between leisure-time physical activity and prevalence of
pain is insufficient. This study investigated associations between frequency, duration, and …
pain is insufficient. This study investigated associations between frequency, duration, and …
Choosing the unit of measurement counts: the use of oral morphine equivalents in studies of opioid consumption is a useful addition to defined daily doses
…, K Hamunen, A Mellbye, O Dale - Palliative …, 2011 - journals.sagepub.com
Aim: Defined daily dose (DDD) is the most common measurement unit used in drug consumption
studies. The DDD for opioids may not reflect their relative clinical potencies. The aim of …
studies. The DDD for opioids may not reflect their relative clinical potencies. The aim of …
Estimating the prevalence of chronic pain: validation of recall against longitudinal reporting (the HUNT pain study)
T Landmark, P Romundstad, O Dale, PC Borchgrevink… - PAIN®, 2012 - Elsevier
Methods for classifying chronic pain in population studies are highly variable, and prevalence
estimates ranges from 11% to 64%. Limited knowledge about the persistence of pain and …
estimates ranges from 11% to 64%. Limited knowledge about the persistence of pain and …
Morphine glucuronide-to-morphine plasma ratios are unaffected by the UGT2B7 H268Y and UGT1A1*28 polymorphisms in cancer patients on chronic morphine …
…, K Zahlsen, PC Borchgrevink, L Hagen, O Dale… - European journal of …, 2002 - Springer
Heading Abstract Objective. UDP-glucuronosyltransferase (UGT) 2B7 is the major UGT isoform
responsible for the 3- and 6-glucuronidation of morphine in humans. Studies in rats have …
responsible for the 3- and 6-glucuronidation of morphine in humans. Studies in rats have …
Associations between physical activity and physical and mental health--a HUNT 3 study.
…, T Landmark, S Kaasa, OLA Dale… - Medicine and science …, 2011 - europepmc.org
Purpose Health-related quality of life (HRQoL) has been characterized as the ultimate goal
for health interventions such as physical activity (PA). We assessed how frequency, duration, …
for health interventions such as physical activity (PA). We assessed how frequency, duration, …
[HTML][HTML] Do CYP2D6 genotypes reflect oxycodone requirements for cancer patients treated for cancer pain? A cross-sectional multicentre study
…, K Bjordal, S Lundström, S Kaasa, O Dale - European journal of …, 2012 - Springer
Objective Opioids are recommended by the World Health Organization for moderate to severe
cancer pain. Oxycodone is one of the most commonly used opioids and is metabolized in …
cancer pain. Oxycodone is one of the most commonly used opioids and is metabolized in …
[HTML][HTML] Take-home naloxone for the emergency interim management of opioid overdose: the public health application of an emergency medicine
Naloxone is a well-established essential medicine for the treatment of life-threatening heroin/opioid
overdose in emergency medicine. Over two decades, the concept of ‘take-home …
overdose in emergency medicine. Over two decades, the concept of ‘take-home …