Effects of age on left ventricular dimensions and filling dynamics in 117 normal persons

AL Klein, DJ Burstow, AJ Tajik, PK Zachariah… - Mayo Clinic …, 1994 - Elsevier
Objective To determine standard left ventricular Doppler measurements in a large reference
group of various ages to reflect the senescence process. Design We prospectively studied …

Age-related prevalence of valvular regurgitation in normal subjects: a comprehensive color flow examination of 118, volunteers

AL Klein, DJ Burstow, AJ Tajik, PK Zachariah… - Journal of the American …, 1990 - Elsevier
We prospectively assessed the influence of aging on the prevalence of valvular regurgitation
by using color flow imaging. One hundred eighteen healthy volunteers (21 to 82 years old) …

Determination of left ventricular mass by echocardiography in a normal population: effect of age and sex in addition to body size

C SHUB, AL KLEIN, PK ZACHARIAH, KR BAILEY… - Mayo Clinic …, 1994 - Elsevier
Objective In this study, we determined the effect of age, sex, and body size on left ventricular
mass. Design Two-dimensional-guided M-mode echocardiography was used in an …

Blood pressure load—a better determinant of hypertension

PK ZACHARIAH, SG SHEPS, DM ILSTRUP… - Mayo Clinic …, 1988 - Elsevier
Noninvasive ambulatory blood pressure monitoring was used to evaluate the diagnosis of
hypertension in 168 untreated patients with essential hypertension. On the basis of overall …

Pathophysiology of peritoneal fluid eosinophilia in peritoneal dialysis patients

…, WE Haley, MJ Goalen, S Todd, PK Zachariah - Nephron, 1999 - karger.com
The finding of an abnormally high number of eosinophils in the peritoneum is a curious
phenomenon, the cause and importance of which are not fully understood. Classically, peritoneal …

The clinical utility of blood pressure load in hypertension

PK Zachariah, WE Sumner III - American journal of hypertension, 1993 - academic.oup.com
The variability of blood pressure and its consequences suggests that ambulatory blood
pressure (ABP) data should be analyzed not only by mean ambulatory blood pressure (MABP), …

Pharmacodynamics of midodrine, an antihypotensive agent

PK Zachariah, DC Bloedow, TP Moyer… - Clinical …, 1986 - Wiley Online Library
Midodrine is an orally active adrenergic agonist useful in the treatment of hypotension. We
have investigated the pharmacodynamics of its active metabolite after oral midodrine therapy …

Age-related characteristics of ambulatory blood pressure load and mean blood pressure in normotensive subjects

PK Zachariah, SG Sheps, KR Bailey, CM Wiltgen… - JAMA, 1991 - jamanetwork.com
Ambulatory blood pressure monitoring has become increasingly popular for diagnosing and
treating hypertension. However, data from normotensive subjects are needed for …

Hypertension and left ventricular diastolic function

RFJ SHEPHERD, PK ZACHARIAH, C SHUB - Mayo Clinic Proceedings, 1989 - Elsevier
In recent years, there has been increased recognition of the relative importance of abnormalities
of diastolic function in patients with essential hypertension. Indeed, diastolic dysfunction …

The effects of antioxidants on the metabolism and mutagenicity of benzo [a] pyrene in vitro.

AD Rahimtula, PK Zachariah, PJ O'Brien - Biochemical Journal, 1977 - ncbi.nlm.nih.gov
Antioxidants inhibit the rat liver microsomal mixed-function-oxidase-catalysed hydroxylation
of benzo [a] pyrene. These antioxidants also decrease the formation of mutagenic products …