User profiles for P. Swiatek

Piotr Świątek

Wroclaw Medical University
Verified email at umed.wroc.pl
Cited by 1085

Chemical structure of phenothiazines and their biological activity

A Jaszczyszyn, K Gąsiorowski, P Świątek… - Pharmacological …, 2012 - Springer
… exert diverse biological activities, which account for their cancer chemopreventive-effect,
as: calmodulin- and protein kinase C inhibitory-actions, anti-proliferative effect, inhibition of P-…

[HTML][HTML] 1, 2, 4-Triazoles as important antibacterial agents

M Strzelecka, P Świątek - Pharmaceuticals, 2021 - mdpi.com
… The azomethine derivatives 1a–g were found to be highly active against P. aeruginosa with
MIC of 16 µg/mL. Among triazolothiadiazoles, compound 2 with chloro-substituent at the 2-…

[HTML][HTML] Antimicrobial activity of 1, 3, 4-oxadiazole derivatives

T Glomb, P Świątek - International journal of molecular sciences, 2021 - mdpi.com
… The most active derivatives shown as a general structure 6 in Figure 4 turned out to be
stronger than the reference drug ampicillin against P. aeruginosa and S. aureus strains. …

Notch1 is essential for postimplantation development in mice.

PJ Swiatek, CE Lindsell, FF Del Amo… - Genes & …, 1994 - genesdev.cshlp.org
The Notch gene of Drosophila encodes a large transmembrane protein involved in cell fate
determination during embryonic and larval development. This gene is evolutionarily …

Perinatal lethality and defects in hindbrain development in mice homozygous for a targeted mutation of the zinc finger gene Krox20.

PJ Swiatek, T Gridley - Genes & development, 1993 - genesdev.cshlp.org
… PJ Swiatek and … P. 1988. A gene encoding a protein with zinc fingers is activated during
G0/G1 transition … P. 1992. Mapping functional regions of the segment-specific transcription factor …

[PDF][PDF] Disruption of the Diaphanous-related formin Drf1 gene encoding mDia1 reveals a role for Drf3 as an effector for Cdc42

J Peng, BJ Wallar, A Flanders, PJ Swiatek, AS Alberts - Current Biology, 2003 - cell.com
Background: Mammalian Diaphanous-related formins (Drfs) act as Rho small GTPase effectors
during growth factor-induced cytoskeletal remodeling and cell division. While both p140 …

Fibronectin matrix assembly enhances adhesion-dependent cell growth

J Sottile, DC Hocking, PJ Swiatek - Journal of cell science, 1998 - journals.biologists.com
… Coverslips were mounted onto dishes in p-phenylenediamine in Small’s buffer. Cells were
examined using an Olympus microscope equipped with epifluorescence, and photographed …

Detection of DNA Copy Number Changes and Oncogenic Signaling Abnormalities from Gene Expression Data Reveals MYC Activation in High-Grade Papillary …

KA Furge, J Chen, J Koeman, P Swiatek, K Dykema… - Cancer research, 2007 - AACR
… Finally, in this report, P-GSEA was used to gain biological insights into both DNA copy
number changes and deregulated signal transduction pathways. Although we have shown that …

Evidence that MIG-6 is a tumor-suppressor gene

YW Zhang, B Staal, Y Su, P Swiatek, P Zhao, B Cao… - Oncogene, 2007 - nature.com
Mitogen-inducible gene 6 (MIG-6) is located in human chromosome 1p36, a locus frequently
associated with human lung cancer. MIG-6 is a negative regulator of epidermal growth …

[HTML][HTML] Anti-cancer activity of derivatives of 1, 3, 4-oxadiazole

T Glomb, K Szymankiewicz, P Świątek - Molecules, 2018 - mdpi.com
Compounds containing 1,3,4-oxadiazole ring in their structure are characterised by multidirectional
biological activity. Their anti-proliferative effects associated with various mechanisms…