Studies on the correlation between size and relative degradation rate of soluble proteins

JF Dice, PJ Dehlinger, RT Schimke - Journal of Biological Chemistry, 1973 - ASBMB
There is a general correlation between the relative degradation rate and the size of soluble
proteins from rat liver. The subunit size rather than the multimer size appears to influence the …

Size distribution of membrane proteins of rat liver and their relative rates of degradation

PJ Dehlinger, RT Schimke - Journal of Biological Chemistry, 1971 - Elsevier
The proteins associated with various membrane fractions, including smooth and rough
endoplasmic reticulum, plasma membrane, and mitochondria of rat liver, were solubilized with …

Effect of size on the relative rate of degradation of rat liver soluble proteins

PJ Dehlinger, RT Schimke - Biochemical and Biophysical Research …, 1970 - Elsevier
A double isotope method was used to determine the relative turnover rates of soluble
proteins of rat liver. The proteins of the supernatant fraction were separated on Sephadex G-200 …

Effects of phenobarbital, 3-methylcholanthrene, and hematin on the synthesis of protein components of rat liver microsomal membranes

PJ Dehlinger, RT Schimke - Journal of Biological Chemistry, 1972 - Elsevier
Smooth endoplasmic reticulum was solubilized in sodium dodecyl sulfate and the protein
components were fractionated by acrylamide gel electrophoresis. The relative rates of amino …

Lipid Binding to the Amphipathic Membrane Protein Cytochrome b5

PJ Dehlinger, PC Jost… - Proceedings of the …, 1974 - National Acad Sciences
The lipid binding properties of the membrane protein cytochrome b 5 (detergent-extracted
from calf liver microsomal preparations) were characterized by studying the interaction of spin-…

[PDF][PDF] The synthesis and degradation of membrane proteins

JM TAYLOR, PJ DEHLINGER, JF DICE… - Drug Metabolism …, 1973 - wxjs.chinayyhg.com
Many studies in recent years have led to the concept that cellular membranes exist as a
dynamic mosaic of proteins, lipids, and carbohydrates. Recent contributions from our laboratory …

Amino acid control of stable RNA synthesis in Friend leukemia cells in relation to intracellular purine nucleoside triphosphate levels

PJ Dehlinger, TA Hamilton, M Litt - European Journal of …, 1977 - Wiley Online Library
Histidinol is known to cause deacylation of histidyl‐tRNA in cultured mammalian cells, thereby
producing a functional deprivation of histidine. Such deprivation of an essential amino …

Not-so-Radical Proposal for Selecting Radical Substitutions in Markush-Type Claims

PJ Dehlinger - J. Pat. & Trademark Off. Soc'y, 1992 - HeinOnline
In the usual invention involving radical substitutions, the inventor will have made and tested
a modest number of compounds with different substitutions. The task of the patent …

Patent Watch: Powering Biomedical Microdevices

PJ Dehlinger - Biomedical Microdevices, 1999 - search.proquest.com
Biomedical microdevices with active-response elements will need electrical powerDHthat is,
a source of current or voltageDHfor their operation. The challenge will be to devise power …

Patent Guide for Miniaturists

PJ Dehlinger - Biomedical Microdevices, 1999 - Springer
Inventors who are mystified by the concepts of “nonobviousness” and “enablement” may be
surprised to find that the two concepts have a simple explanation in information theory. …