Safety, tolerability, and immunogenicity of an inactivated SARS-CoV-2 vaccine (CoronaVac) in healthy adults aged 60 years and older: a randomised, double-blind …
Z Wu, Y Hu, M Xu, Z Chen, W Yang, Z Jiang… - The Lancet Infectious …, 2021 - thelancet.com
Background A vaccine against COVID-19 is urgently needed for older adults, in whom
morbidity and mortality due to the disease are increased. We aimed to assess the safety, …
morbidity and mortality due to the disease are increased. We aimed to assess the safety, …
Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease
…, Y Li, L Zhao, H Li, X Zhou, L Chen, D Liu, J Chen… - Nature …, 2012 - nature.com
We performed a meta-analysis of 2 genome-wide association studies of coronary artery
disease comprising 1,515 cases and 5,019 controls followed by replication studies in 15,460 …
disease comprising 1,515 cases and 5,019 controls followed by replication studies in 15,460 …
[HTML][HTML] Spatially resolved multi-omics highlights cell-specific metabolic remodeling and interactions in gastric cancer
C Sun, A Wang, Y Zhou, P Chen, X Wang… - Nature …, 2023 - nature.com
Mapping tumor metabolic remodeling and their spatial crosstalk with surrounding non-tumor
cells can fundamentally improve our understanding of tumor biology, facilitates the …
cells can fundamentally improve our understanding of tumor biology, facilitates the …
[HTML][HTML] The cleavage of gasdermin D by caspase-11 promotes tubular epithelial cell pyroptosis and urinary IL-18 excretion in acute kidney injury
…, D Xu, J Yin, B Wang, Z Zhou, Q Cheng, P Chen… - Kidney international, 2019 - Elsevier
Inflammation and tubular cell death are the hallmarks of acute kidney injury. However, the
precise mechanism underlying these effects has not been fully elucidated. Here we tested …
precise mechanism underlying these effects has not been fully elucidated. Here we tested …
[HTML][HTML] SIRT1 ameliorates age-related senescence of mesenchymal stem cells via modulating telomere shelterin
H Chen, X Liu, W Zhu, H Chen, X Hu, Z Jiang… - Frontiers in aging …, 2014 - frontiersin.org
Mesenchymal stem cells (MSCs) senescence is an age-related process that impairs the
capacity for tissue repair and compromises the clinical use of autologous MSCs for tissue …
capacity for tissue repair and compromises the clinical use of autologous MSCs for tissue …
[HTML][HTML] Applicability of personal laser scanning in forestry inventory
Light Detection and Ranging (LiDAR) technology has been widely used in forestry surveys
in the form of airborne laser scanning (ALS), terrestrial laser scanning (TLS), and mobile …
in the form of airborne laser scanning (ALS), terrestrial laser scanning (TLS), and mobile …
[HTML][HTML] SIRT6 as a key event linking P53 and NRF2 counteracts APAP-induced hepatotoxicity through inhibiting oxidative stress and promoting hepatocyte …
…, W Li, P Chen, Y Jiang, J Sun, Y Chen, P Chen… - … Pharmaceutica Sinica B, 2021 - Elsevier
Acetaminophen (APAP) overdose is the leading cause of drug-induced liver injury, and its
prognosis depends on the balance between hepatocyte death and regeneration. Sirtuin 6 (…
prognosis depends on the balance between hepatocyte death and regeneration. Sirtuin 6 (…
Stem Leydig cells in the adult testis: characterization, regulation and potential applications
P Chen, BR Zirkin, H Chen - Endocrine Reviews, 2020 - academic.oup.com
Androgen deficiency (hypogonadism) affects males of all ages. Testosterone replacement
therapy (TRT) is effective in restoring serum testosterone and relieving symptoms. TRT, …
therapy (TRT) is effective in restoring serum testosterone and relieving symptoms. TRT, …
[HTML][HTML] Comparison of the binding interactions of 4-hydroxyphenylpyruvate dioxygenase inhibitor herbicides with humic acid: Insights from multispectroscopic …
P Chen, M Shi, X Liu, X Wang, M Fang, Z Guo… - Ecotoxicology and …, 2022 - Elsevier
4-Hydroxyphenylpyruvate dioxygenase (HPPD) inhibitor is one of the important herbicides
to solve the problem of weed control. With the widespread and continued use of HPPD …
to solve the problem of weed control. With the widespread and continued use of HPPD …
[HTML][HTML] Six-month follow-up of a booster dose of CoronaVac in two single-centre phase 2 clinical trials
…, X Chen, B Han, K Chu, Y Song, H Jin, P Chen… - Nature …, 2022 - nature.com
Determining the duration of immunity induced by booster doses of CoronaVac is crucial for
informing recommendations for booster regimens and adjusting immunization strategies. In …
informing recommendations for booster regimens and adjusting immunization strategies. In …