User profiles for R. A. Urbanowicz
Richard UrbanowiczLecturer in Infection Immunology, University of Liverpool Verified email at liverpool.ac.uk Cited by 2271 |
Evaluation of fresh and cryopreserved hepatocytes as in vitro drug metabolism tools for the prediction of metabolic clearance
DF McGinnity, MG Soars, RA Urbanowicz… - Drug metabolism and …, 2004 - ASPET
The intrinsic clearances (CL int ) of 50 neutral and basic marketed drugs were determined
in fresh human hepatocytes and the data used to predict human in vivo hepatic metabolic …
in fresh human hepatocytes and the data used to predict human in vivo hepatic metabolic …
[PDF][PDF] Human adaptation of Ebola virus during the West African outbreak
The 2013–2016 outbreak of Ebola virus (EBOV) in West Africa was the largest recorded. It
began following the cross-species transmission of EBOV from an animal reservoir, most likely …
began following the cross-species transmission of EBOV from an animal reservoir, most likely …
Two doses of the SARS-CoV-2 BNT162b2 vaccine enhance antibody responses to variants in individuals with prior SARS-CoV-2 infection
RA Urbanowicz, T Tsoleridis, HJ Jackson… - Science translational …, 2021 - science.org
Understanding the impact of prior infection with severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) on the response to vaccination is a priority for responding to the …
coronavirus 2 (SARS-CoV-2) on the response to vaccination is a priority for responding to the …
Quantitative validation and comparison of multiplex cytokine kits
JL Richens, RA Urbanowicz, R Metcalf… - Journal of …, 2010 - journals.sagepub.com
The focus of biomarker studies is shifting toward deciphering patterns of biomolecules as
they provide a more comprehensive depiction of disease than individual biomarkers. …
they provide a more comprehensive depiction of disease than individual biomarkers. …
[HTML][HTML] Enhanced effector function of cytotoxic cells in the induced sputum of COPD patients
RA Urbanowicz, JR Lamb, I Todd, JM Corne… - Respiratory …, 2010 - Springer
… (CD45RO + RA - ) and a reduction in the proportion of naïve cells (CD45RO - RA + )
compared to the other two groups (Figure 2A). The proportion of T EMRA cells (CD45RO + RA + ) …
compared to the other two groups (Figure 2A). The proportion of T EMRA cells (CD45RO + RA + ) …
[HTML][HTML] Hepatitis C virus vaccine: challenges and prospects
The hepatitis C virus (HCV) causes both acute and chronic infection and continues to be a
global problem despite advances in antiviral therapeutics. Current treatments fail to prevent …
global problem despite advances in antiviral therapeutics. Current treatments fail to prevent …
[HTML][HTML] Immunogenicity of a new gorilla adenovirus vaccine candidate for COVID-19
…, A Lahm, A Sommella, AM Contino, RA Urbanowicz… - Molecular Therapy, 2021 - cell.com
The coronavirus disease 2019 (COVID-19) pandemic caused by the emergent severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) threatens global public health, and there …
respiratory syndrome coronavirus 2 (SARS-CoV-2) threatens global public health, and there …
An alpaca nanobody inhibits hepatitis C virus entry and cell-to-cell transmission
…, L Meredith, L Damier-Piolle, RA Urbanowicz… - Hepatology, 2013 - journals.lww.com
Severe liver disease caused by chronic hepatitis C virus is the major indication for liver
transplantation. Despite recent advances in antiviral therapy, drug toxicity and unwanted side …
transplantation. Despite recent advances in antiviral therapy, drug toxicity and unwanted side …
[HTML][HTML] Inflammasome contribution to the activation of Th1, Th2, and Th17 immune responses
E Martynova, A Rizvanov, RA Urbanowicz… - Frontiers in …, 2022 - frontiersin.org
Inflammasomes are cytosolic polyprotein complexes formed in response to various external
and internal stimuli, including viral and bacterial antigens. The main product of the …
and internal stimuli, including viral and bacterial antigens. The main product of the …
Antigenicity and immunogenicity of differentially glycosylated hepatitis C virus E2 envelope proteins expressed in mammalian and insect cells
RA Urbanowicz, R Wang, JE Schiel, Z Keck… - Journal of …, 2019 - Am Soc Microbiol
The development of a prophylactic vaccine for hepatitis C virus (HCV) remains a global health
challenge. Cumulative evidence supports the importance of antibodies targeting the HCV …
challenge. Cumulative evidence supports the importance of antibodies targeting the HCV …