[PDF][PDF] Abyssomicin CA polycyclic antibiotic from a marine Verrucosispora strain as an inhibitor of the p-aminobenzoic acid/tetrahydrofolate biosynthesis pathway

…, H Zahner, HP Fiedler, RD Sussmuth - Angewandte Chemie …, 2004 - academia.edu
For many multiresistant Gram-positive bacteria, for example, methicillin-resistant Staphylococcus
aureus strains (MRSA), vancomycin-or teicoplanin-type glycopeptide antibiotics are the …

Abyssomicins, inhibitors of the para-aminobenzoic acid pathway produced by the marine Verrucosispora strain AB-18-032

…, B Bister, D Bischoff, RD SüSSMUTH… - The Journal of …, 2004 - jstage.jst.go.jp
A screening method was established to detect inhibitors of the biosynthetic pathways of
aromatic amino acids and para-aminobenzoic acid, the precursor of folic acid, using an agar …

Plantazolicin, a Novel Microcin B17/Streptolysin S-Like Natural Product from Bacillus amyloliquefaciens FZB42

…, J Vater, AL Markley, RD Süssmuth… - Journal of …, 2011 - Am Soc Microbiol
Here we report on a novel thiazole/oxazole-modified microcin (TOMM) from Bacillus
amyloliquefaciens FZB42, a Gram-positive soil bacterium. This organism is well known for …

Proximicin A, B and C, novel aminofuran antibiotic and anticancer compounds isolated from marine strains of the actinomycete Verrucosispora

…, W Beil, K Schneider, S Keller, RD Sussmuth - The Journal of …, 2008 - nature.com
A family of three novel aminofuran antibiotics named as proximicins was isolated from the
marine Verrucosispora strain MG-37. Proximicin A was detected in parallel in the marine …

Hantzsch pyrrole synthesis on solid support

AW Trautwein, RD Süßmuth, G Jung - Bioorganic & medicinal chemistry …, 1998 - Elsevier
An efficient method for solid-phase synthesis of pyrroles is described. Polystyrene Rink amide
resin is acetoacetylated and converted into polymer bound enaminones upon treatment …

[PDF][PDF] Heterologous expression, biosynthesis, and mutagenesis of type II lantibiotics from Bacillus licheniformis in Escherichia coli

T Caetano, JM Krawczyk, E Mösker, RD Süssmuth… - Chemistry & biology, 2011 - cell.com
Lichenicidin is a class II two-component lantibiotic produced by Bacillus licheniformis. It is
composed of the two peptides Bliα and Bliβ, which act synergistically against various Gram-…

[HTML][HTML] Crystal structure of OxyB, a cytochrome P450 implicated in an oxidative phenol coupling reaction during vancomycin biosynthesis

…, D Bischoff, B Bister, RD Sussmuth… - Journal of Biological …, 2002 - ASBMB
Gene-inactivation studies point to the involvement of OxyB in catalyzing the first oxidative
phenol coupling reaction during glycopeptide antibiotic biosynthesis. TheoxyB gene has been …

Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature

…, K Sivonen, L Smith, T Stein, RD Süssmuth… - Natural product …, 2013 - pubs.rsc.org
Covering: 1988 to 2012 This review presents recommended nomenclature for the biosynthesis
of ribosomally synthesized and post-translationally modified peptides (RiPPs), a rapidly …

Self-assembled monolayer epitope bridges for molecular imprinting and cancer biomarker sensing

J Drzazgowska, B Schmid, RD Süssmuth… - Analytical …, 2020 - ACS Publications
The research in biomedicine, cell signaling, diagnostics, and biocatalysis rely on selective
protein binders that specifically capture a protein in a complex medium for either preparative …

[PDF][PDF] Glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908: function of a halogenase and a haloperoxidase/perhydrolase

…, D Bischoff, J Recktenwald, G Jung, RD Süßmuth… - Chemistry & biology, 2002 - cell.com
Glycopeptides are important clinical emergency antibiotics consisting of a glycosylated and
chlorinated heptapeptide backbone. The understanding of the biosynthesis is crucial for …