As a result of its broad substrate specificity and critical localization in excretory and barrier
function tissues, P-glycoprotein (P-gp) plays major roles in the pharmacokinetics, safety and …

The efflux transporter P-glycoprotein, expressed at high levels at the blood-brain barrier,
exerts a profound effect on the disposition of various therapeutic compounds in the brain. A …

Central nervous system diseases represent a huge world of burden of human suffering with
negative economic results. Most therapeutic compounds cannot attain the brain because of …

This paper extends the study of steady siphon flows in isolated magnetic flux tubes surrounded
by field-free gas to the case of adiabatic flows. The basic equations governing steady …

Aim To identify, compare and contrast the major component parts of heterogeneous stratified
sample of nursing legislation. Background Nursing legislation varies from one jurisdiction …

… (black cells in the matrix are those present in the RN but not in the FN, as we explain next). …
In this toy example, the entries of the RN have been transformed into transition probabilities …

The objective of this research was to evaluate how the use of mathematical models that simulate
the drugs pharmacokinetic, can influence the calculation of pharmacokinetic parameters…

… A convenience sample of 979 registered nurses from seven Magnet® certified hospitals
within a healthcare system in South Florida participated in the study. A modified version of The …

Background UCBT has proven effective in treating patients with hematologic malignancies (HM),but
engraftment is slower and graft failure rates higher compared to other unrelated …

… Benton (RN, MPhil) identified the need for this study and conceptualised the problem. He
also did the policy analysis and wrote the initial draft. Máximo Antonio González-Jurado (…