Chemical biology of nitric oxide: regulation and protective and toxic mechanisms

…, I Hanbauer, MB Grisham, F Laval, RW Nims… - Current topics in cellular …, 1996 - Elsevier
Publisher Summary This chapter discusses the important aspects of the solution chemistry
of nitrogen oxide (NO) and reactive nitrogen oxide species (RNOS), biochemical targets of …

[HTML][HTML] Recommendation of short tandem repeat profiling for authenticating human cell lines, stem cells, and tissues

…, M Nardone, RM Nardone, RW Nims… - In Vitro Cellular & …, 2010 - Springer
Cell misidentification and cross-contamination have plagued biomedical research for as
long as cells have been employed as research tools. Examples of misidentified cell lines …

“NONOates”(1-substituted diazen-1-ium-1, 2-diolates) as nitric oxide donors: convenient nitric oxide dosage forms

LK Keefer, RW Nims, KM Davies, DA Wink - Methods in enzymology, 1996 - Elsevier
Substituted diazen-1-ium-1,2-diolates have proved useful as tools in enzymology and other
pharmacological research applications in which spontaneous generation of nitric oxide …

Reactions of the bioregulatory agent nitric oxide in oxygenated aqueous media: Determination of the kinetics for oxidation and nitrosation by intermediates generated …

DA Wink, JF Darbyshire, RW Nims… - Chemical research in …, 1993 - ACS Publications
A recent discovery in mammalian biology has been the important physiological role that
nitric oxide plays in blood pressure regulation, neurotransmission, macrophage-in-duced …

[HTML][HTML] Short tandem repeat profiling: part of an overall strategy for reducing the frequency of cell misidentification

RW Nims, G Sykes, K Cottrill, P Ikonomi… - In Vitro Cellular & …, 2010 - Springer
The role of cell authentication in biomedical science has received considerable attention,
especially within the past decade. This quality control attribute is now beginning to be given …

Dealkylation of pentoxyresorufin: a rapid and sensitive assay for measuring induction of cytochrome (s) P-450 by phenobarbital and other xenobiotics in the rat

RA Lubet, RT Mayer, JW Cameron, RW Nims… - Archives of biochemistry …, 1985 - Elsevier
The O-dealkylation of pentoxyresorufin (7-pentoxyphenoxazone) by rat liver microsomes was
examined. The reaction appeared highly specific for certain phenobarbital inducible forms …

Reaction kinetics for nitrosation of cysteine and glutathione in aerobic nitric oxide solutions at neutral pH. Insights into the fate and physiological effects of …

DA Wink, RW Nims, JF Darbyshire… - Chemical research in …, 1994 - ACS Publications
Asno=(6±2) X 106 M™ 2 s-1, a value identical to that forthe formation of reactive intermediates
in the autoxidation of NO. Competition studies performed with a variety of aminoacids, …

Extraction, stability, and quantitation of ellagic acid in various fruits and nuts

…, AS Krupnick, YH Heur, JA Blinzler, RW Nims… - Journal of food …, 1989 - Elsevier
This study was undertaken to determine the amount of ellagic acid, a naturally occurring
inhibitor of carcinogenesis, in various fruits and nuts. Ellagic acid was extracted from freeze-…

Inhibition of cytochromes P450 by nitric oxide and a nitric oxide-releasing agent

…, CR Jones, SC Eshenaur, RW Nims - Archives of biochemistry …, 1993 - Elsevier
The effect of nitric oxide (NO) on cytochrome P450-mediated benzyloxyresorufin and
ethoxyresorufin O-dealkylase activity of rat hepatic postmitochondrial (S-9) or microsomal …

Match criteria for human cell line authentication: where do we draw the line?

…, Y Nakamura, E Elmore, RW Nims… - … journal of cancer, 2013 - Wiley Online Library
Continuous human cell lines have been used extensively as models for biomedical research.
In working with these cell lines, researchers are often unaware of the risk of cross‐…