User profiles for R. Sawamura

Regina Sawamura

Professor de Pediatria, Faculdade de Medicina de Ribeirão Preto USP
Verified email at fmrp.usp.br
Cited by 520

Induction of DNA damage by dimethylarsine, a metabolite of inorganic arsenics, is for the major part likely due to its peroxyl radical

…, M Hoshino, M Okamoto, R Sawamura… - Biochemical and …, 1990 - Elsevier
To reveal the mechanisms of previously reported lung-specific DNA strand scissions in murine
after oral administration of dimethylarsinic acid (DMAA), a main metabolite of inorganic …

Cellular response to oxidative damage in lung induced by the administration of dimethylarsinic acid, a major metabolite of inorganic arsenics, in mice

K Yamanaka, A Hasegawa, R Sawamura… - Toxicology and applied …, 1991 - Elsevier
Oral administration of dimethylarsinic acid (DMAA), a major metabolite of inorganic arsenics,
induces DNA damage in the mouse and rat lung due to both active oxygens and …

Predictability of idiosyncratic drug toxicity risk for carboxylic acid-containing drugs based on the chemical stability of acyl glucuronide

R Sawamura, N Okudaira, K Watanabe, T Murai… - Drug metabolism and …, 2010 - ASPET
Acyl glucuronides (AGs) formed from carboxylic acid-containing drugs have been considered
to be a cause of idiosyncratic drug toxicity (IDT). Chemical stability of AGs is supposed to …

[HTML][HTML] Oral aspects in celiac disease children: clinical and dental enamel chemical evaluation

…, AM de Queiroz, RAB da Silva, R Sawamura… - Oral surgery, oral …, 2015 - Elsevier
Objective The aim of this study was to evaluate the oral manifestations of celiac disease (CD),
the chemical composition of dental enamel, and the occurrence of CD in children with …

Dimethylated arsenics induce DNA strand breaks in lung via the production of active oxygen in mice

K Yamanaka, A Hasegawa, R Sawamura… - Biochemical and …, 1989 - Elsevier
In order to study the genotoxicity of arsenics, we focused our attention on dimethylarsinic
acid (DMAA) which was a main metabolite of inorganic arsenics in mammals. ICR mice were …

[HTML][HTML] Efficacy of Brazilian propolis against herpes simplex virus type 1 infection in mice and their modes of antiherpetic efficacies

…, Y Takamori, H Kai, R Sawamura… - Evidence-Based …, 2011 - hindawi.com
Ethanol extracts (AF-06, 07, and 08, 10 mg/kg) of Brazilian propolis were administered orally
to cutaneously herpes simplex virus type 1 (HSV-1)-infected mice three times daily on days …

Effects of tetrabromobisphenol A, a brominated flame retardant, on the immune response to respiratory syncytial virus infection in mice

W Watanabe, T Shimizu, R Sawamura, A Hino… - International …, 2010 - Elsevier
Effects of the brominated flame retardants (BFRs), decabrominated diphenyl ether (DBDE),
hexabromocyclododecane (HBCD), and tetrabromobisphenol A (TBBPA), on host immunity …

[HTML][HTML] Acrodermatitis enteropathica: clinical manifestations and pediatric diagnosis

IRLD Ciampo, R Sawamura, LAD Ciampo… - Revista Paulista de …, 2018 - SciELO Brasil
Objetivo: Relatar um caso de acrodermatite enteropática, doença rara com herança
autossômica recessiva. Relato de caso: Menino de 11 meses de idade apresentava lesões …

[HTML][HTML] Antiviral activities of diarylheptanoids against influenza virus in vitro

R Sawamura, Y Sun, K Yasukawa, T Shimizu… - Journal of natural …, 2010 - Springer
The anti-influenza A/PR/8/34 (H1N1) virus activities of ten diarylheptanoids isolated from
Alpinia officinarum were examined using the MTT method. The 50% inhibitory concentration of …

In Vitro and in Vivo Anti-Influenza Virus Activity of Diarylheptanoids Isolated from Alpinia Officinarum

R Sawamura, T Shimizu, Y Sun… - Antiviral Chemistry …, 2010 - journals.sagepub.com
… Ly TN, Shimoyamada M, Kato K, Yamauchi R. Isolation and characterization of some antioxidative
compounds from the rhizomes of smaller galanga (Alpinia officinarum … Rie Sawamura