“NONOates”(1-substituted diazen-1-ium-1, 2-diolates) as nitric oxide donors: convenient nitric oxide dosage forms

LK Keefer, RW Nims, KM Davies, DA Wink - Methods in enzymology, 1996 - Elsevier
Substituted diazen-1-ium-1,2-diolates have proved useful as tools in enzymology and other
pharmacological research applications in which spontaneous generation of nitric oxide …

Reactions of the bioregulatory agent nitric oxide in oxygenated aqueous media: Determination of the kinetics for oxidation and nitrosation by intermediates generated …

DA Wink, JF Darbyshire, RW Nims… - Chemical research in …, 1993 - ACS Publications
A recent discovery in mammalian biology has been the important physiological role that
nitric oxide plays in blood pressure regulation, neurotransmission, macrophage-in-duced …

Dealkylation of pentoxyresorufin: a rapid and sensitive assay for measuring induction of cytochrome (s) P-450 by phenobarbital and other xenobiotics in the rat

RA Lubet, RT Mayer, JW Cameron, RW Nims… - Archives of biochemistry …, 1985 - Elsevier
The O-dealkylation of pentoxyresorufin (7-pentoxyphenoxazone) by rat liver microsomes was
examined. The reaction appeared highly specific for certain phenobarbital inducible forms …

Reaction kinetics for nitrosation of cysteine and glutathione in aerobic nitric oxide solutions at neutral pH. Insights into the fate and physiological effects of …

DA Wink, RW Nims, JF Darbyshire… - Chemical research in …, 1994 - ACS Publications
Asno=(6±2) X 106 M™ 2 s-1, a value identical to that forthe formation of reactive intermediates
in the autoxidation of NO. Competition studies performed with a variety of aminoacids, …

Extraction, stability, and quantitation of ellagic acid in various fruits and nuts

…, AS Krupnick, YH Heur, JA Blinzler, RW Nims… - Journal of food …, 1989 - Elsevier
This study was undertaken to determine the amount of ellagic acid, a naturally occurring
inhibitor of carcinogenesis, in various fruits and nuts. Ellagic acid was extracted from freeze-…

Chemical biology of nitric oxide: regulation and protective and toxic mechanisms

…, I Hanbauer, MB Grisham, F Laval, RW Nims… - Current topics in cellular …, 1996 - Elsevier
Publisher Summary This chapter discusses the important aspects of the solution chemistry
of nitrogen oxide (NO) and reactive nitrogen oxide species (RNOS), biochemical targets of …

Match criteria for human cell line authentication: where do we draw the line?

…, Y Nakamura, E Elmore, RW Nims… - … journal of cancer, 2013 - Wiley Online Library
Continuous human cell lines have been used extensively as models for biomedical research.
In working with these cell lines, researchers are often unaware of the risk of cross‐…

[HTML][HTML] Assessment of a respiratory face mask for capturing air pollutants and pathogens including human influenza and rhinoviruses

SS Zhou, S Lukula, C Chiossone, RW Nims… - Journal of thoracic …, 2018 - ncbi.nlm.nih.gov
Background Prevention of infection with airborne pathogens and exposure to airborne
particulates and aerosols (environmental pollutants and allergens) can be facilitated through use …

Methoxyresorufin and benzyloxyresorufin: substrates preferentially metabolized by cytochromes P4501A2 and 2B, respectively, in the rat and mouse

PV Nerurkar, SS Park, PE Thomas, RW Nims… - Biochemical …, 1993 - Elsevier
The cytochrome P450 isozyme specificity for the O-dealkylation of methoxyresorufin (MTR)
and benzyloxyresorufin (BZR) in the rat and mouse was investigated. The induction of …

[HTML][HTML] Recommendation of short tandem repeat profiling for authenticating human cell lines, stem cells, and tissues

…, M Nardone, RM Nardone, RW Nims… - In Vitro Cellular & …, 2010 - Springer
Cell misidentification and cross-contamination have plagued biomedical research for as
long as cells have been employed as research tools. Examples of misidentified cell lines …