Hepatitis C virus (HCV) infection is a serious cause of chronic liver disease worldwide with
more than 170 million infected individuals at risk of developing significant morbidity and …

ContextAttachment of most rhinovirus subtypes to cells depends on a cellular receptor, the
intercellular adhesion molecule 1 (ICAM-1). A recombinant soluble ICAM-1 (tremacamra, …

Hepatocytes provide an integrated model to study drug metabolism and disposition. As a
result of a loss of polarity or a significant decrease in the expression of enzymes and …

Importance Compared with non-Hispanic White individuals, African American individuals
from the same community are approximately twice as likely to develop Alzheimer disease. …

The pharmacokinetics, mass balance, and metabolite profiles of faldaprevir, a selective
peptide-mimetic hepatitis C virus NS3/NS4 protease inhibitor, were assessed at steady state in 7 …

In this Letter, the'Competing interests statement'should be corrected to:'The authors declare
competing financial interests: RES was the clinical investigator and received an honorarium …

Hepatocytes provide an integrated model to study drug metabolism and disposition. Suspended
and sandwich cultured hepatocytes have limitations in determining hepatocellular drug …

The metabolism, pharmacokinetics, excretion and tissue distribution of a hepatitis C NS3/NS4
protease inhibitor, faldaprevir, were studied in rats following a single 2 mg/kg intravenous …

… Is this the origin of the surname "Saint-George" under which he became famous? No … Roger
de Beauvoir, who has written a lengthy novel' with Saint-George for its hero, one filled with …

The Alzheimer Disease Genetics Consortium (ADGC) performed a genome-wide association
study of late-onset Alzheimer disease using a three-stage design consisting of a discovery …