The dose proportionality and pharmacokinetics of loratadine, a new nonsedating
antihistamine, were studied in 12 normal volunteers. In a three‐way cross‐over, each volunteer …

… Using different formulations of griseofulvin, Katchen and Symchowicz [6-81 found a good
correlation in man between dissolution rates in simulated intestinal fluid and the area under …

The excretion of loratadine, a new nonsedating antihistamine, into human breast milk was
studied in six lactating nonpregnant volunteers. Each volunteer received one 40‐mg …

In a three‐way crossover design, 12 healthy male volunteers received 5 × 10 6 IU/m 2 body
surface area interferon α‐2b(IFN α‐2b) by intravenous (IV) infusion over 30 minutes, …

… s-5 Much of the accumulated data demonstrate that other steroids also are associated
with plasma proteins, and exhibit a wide degree of binding. It has also become increasingly …

Single dose and steady‐state pharmacokinetics of flutamide (F) and its active plasma metabolite,
hydroxyflutamide (HF) were studied in twelve healthy geriatric volunteers administered …

The pharmacokinetics and metabolism of 3 H-chlorpheniramine maleate have been studied
in man. After a po dose (12 mg), 3 H appeared rapidly in plasma and at two hours was …

… of maximum plasma concentrations (C,T,aX), and high degree of urinary excretion, in
conjunction with its potent activity against major pathogens including Haemophilus, Branhamella, S…

The pharmacokinetics of loratadine, a non-sedating anti-histamine, were studied in 12
normal geriatric volunteers. In an open label fashion, each volunteer received one 40 mg …

The major urinary metabolite of albuterol in man was isolated and purified by ion-exchange
chromatography and countercurrent distribution. On the basis of proton magnetic resonance, …