Epidemiology of lung cancer: Diagnosis and management of lung cancer: American College of Chest Physicians evidence-based clinical practice guidelines

AJ Alberg, MV Brock, JG Ford, JM Samet, SD Spivack - Chest, 2013 - Elsevier
Background Ever since a lung cancer epidemic emerged in the mid-1900s, the epidemiology
of lung cancer has been intensively investigated to characterize its causes and patterns of …

Human cytochromes P450

…, JR Falck, G Farrell, LS Kaminsky, SD Spivack… - Molecular aspects of …, 1999 - Elsevier
The cytochrome P450 proteins (CYPs) are a family of haem proteins resulting from expression
of a gene super-family that currently contains around 1000 members in species ranging …

Overexpression of the MicroRNA hsa-miR-200c Leads to Reduced Expression of Transcription Factor 8 and Increased Expression of E-Cadherin

GJ Hurteau, JA Carlson, SD Spivack, GJ Brock - Cancer research, 2007 - AACR
MicroRNAs are ∼22-nucleotide sequences thought to interact with multiple mRNAs resulting
in either translational repression or degradation. We previously reported that several …

Single-cell analysis of somatic mutations in human bronchial epithelial cells in relation to aging and smoking

…, Y Peter, A Sadoughi, C Shah, K Ye, SD Spivack… - Nature …, 2022 - nature.com
Although lung cancer risk among smokers is dependent on smoking dose, it remains
unknown if this increased risk reflects an increased rate of somatic mutation accumulation in …

Dietary chemoprevention strategies for induction of phase II xenobiotic-metabolizing enzymes in lung carcinogenesis: a review

XL Tan, SD Spivack - Lung cancer, 2009 - Elsevier
Lung cancer is the leading cause of cancer mortality for men and women in the United States
and is a growing worldwide problem. Protection against lung cancer is associated with …

Gender-dependent expression of alpha and beta estrogen receptors in human nontumor and tumor lung tissue

MJ Fasco, GJ Hurteau, SD Spivack - Molecular and cellular endocrinology, 2002 - Elsevier
Estrogen receptor (ER) expression in human lung has been understudied, particularly in
light of its potential biological importance in the female lung cancer epidemic. Reverse …

Potential mRNA degradation targets of hsa-miR-200c

GJ Hurteau, SD Spivack, GJ Brock - Cell Cycle, 2006 - Taylor & Francis
Using an anchored oligo(dT) based RT-PCR approach we quantified endogenous expression
of ten microRNAs in six cell lines. This identified a miRNA, miR-200c, with variable …

Gene-environment interaction signatures by quantitative mRNA profiling in exfoliated buccal mucosal cells

SD Spivack, GJ Hurteau, R Jain, SV Kumar, KM Aldous… - Cancer research, 2004 - AACR
… Han W, Pentecost BT, Spivack SD. Functional evaluation of novel single nucleotide
polymorphisms and haplotypes in the promoter regions of CYP1B1 and CYP1A1 genes. …

[PDF][PDF] Epidemiology of lung cancer

AJ Alberg, MV Brock, JG Ford, JM Samet, SD Spivack - Chest, 2013 - aamr.org.ar
Background: Ever since a lung cancer epidemic emerged in the mid-1900s, the epidemiology
of lung cancer has been intensively investigated to characterize its causes and patterns of …

Screening for DNA adducts by data-dependent constant neutral loss-triple stage mass spectrometry with a linear quadrupole ion trap mass spectrometer

…, S Langouët, I Yasa, ID Kozekov, SD Spivack… - Analytical …, 2009 - ACS Publications
A two-dimensional linear quadrupole ion trap mass spectrometer (LIT/MS) was employed to
simultaneously screen for DNA adducts of environmental, dietary, and endogenous …