The novel coronavirus disease 2019 (COVID-19), caused by the pathogen severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), originated in Wuhan, China, and has now …

Over the past 20 years, the Global Initiative for Asthma (GINA) has regularly published and
annually updated a global strategy for asthma management and prevention that has formed …

BACKGROUND: Measurement of biomarkers has been incorporated within clinical
research studies of asthma to characterize the population and associate the disease with …

Background It is unknown whether inhaled corticosteroids can modify the subsequent
development of asthma in preschool children at high risk for asthma. Methods We randomly …

Background: The assessment of asthma control is pivotal to the evaluation of treatment
response in individuals and in clinical trials. Previously, asthma control, severity, and …

Background Research has underscored the effects of exposure and sensitization to allergens
on the severity of asthma in inner-city children. It has also revealed the limitations of …

The role of inflammation in the pathogenesis of severe asthma chronically treated with high
doses of glucocorticoids is poorly understood. Despite this, treatment has been aimed at …

… Stanley J Szefler … Kunselman, SC Lazarus, RF Lemanske, RJ Martin, SP Peters, CA
Sorkness, SJ Szefler, and JM Drazen designed the study. E Israel, JG Ford, HA Boushey, A Deykin, …

Background Long-acting beta-agonist (LABA) therapy improves symptoms in patients whose
asthma is poorly controlled by an inhaled glucocorticoid alone. Alternative treatments for …

Background Short-term targeted treatment can potentially prevent fall asthma exacerbations
while limiting therapy exposure. Objective We sought to compare (1) omalizumab with …