User profiles for S. L. Varga

Sergio L Vargas

University of Chile
Verified email at med.uchile.cl
Cited by 3360

On the use of the O-methylmandelate ester for establishment of absolute configuration of secondary alcohols

…, ME Christy, GS Ponticello, SL Varga… - The Journal of …, 1986 - ACS Publications
With the current emphasis on obtaining enantiomerically pure compounds, methods for
resolution, determination of enantiomeric purities, and determination of ab-solute configurations …

Martinelline and martinellic acid, novel G-protein linked receptor antagonists from the tropical plant Martinella iquitosensis (Bignoniaceae)

…, SM Pitzenberger, SL Varga - Journal of the …, 1995 - ACS Publications
Twonovel pyrroloquinoline alkaloids, martinelline (1) and martinellic acid (2), were isolated
from an organic extract of Martinella iquitosensis roots. The ethnobotanical use of the two …

[HTML][HTML] Bivalent prefusion F vaccine in pregnancy to prevent RSV illness in infants

…, LM Huang, LJ Bont, T Otsuki, SL Vargas… - … England Journal of …, 2023 - Mass Medical Soc
Background Whether vaccination during pregnancy could reduce the burden of respiratory
syncytial virus (RSV)–associated lower respiratory tract illness in newborns and infants is …

[HTML][HTML] Phase 3 safety and efficacy of AZD1222 (ChAdOx1 nCoV-19) Covid-19 vaccine

…, S Buchbinder, J Cowden, SL Vargas… - … England Journal of …, 2021 - Mass Medical Soc
Background The safety and efficacy of the AZD1222 (ChAdOx1 nCoV-19) vaccine in a large,
diverse population at increased risk for severe acute respiratory syndrome coronavirus 2 (…

Design and synthesis of potent, selective, and orally bioavailable tetrasubstituted imidazole inhibitors of p38 mitogen-activated protein kinase

…, GR Smith, A Tebben, JP Vacca, SL Varga… - Journal of medicinal …, 1999 - ACS Publications
Novel potent and selective diarylimidazole inhibitors of p38 MAP (mitogen-activated protein)
kinase are described which have activity in both cell-based assays of tumor necrosis factor-…

Practical synthesis of cyclic peptides, with an example of dependence of cyclization yield upon linear sequence

SF Brady, SL Varga, RM Freidinger… - The Journal of …, 1979 - ACS Publications
A convenient general procedure for thesynthesis of cyclic peptides is reported. The linear
intermediates, obtained via solid-phase synthesis, are cyclized by the coupling agent …

Search for Primary Infection by Pneumocystis carinii in a Cohort of Normal, Healthy Infants

SL Vargas, WT Hughes, ME Santolaya… - Clinical infectious …, 2001 - academic.oup.com
To determine whether Pneumocystis carinii is associated with clinical illness in the competent
host, 107 normal, healthy infants were enrolled in a 2-year prospective cohort study in …

Pneumocystis Colonization Is Highly Prevalent in the Autopsied Lungs of the General Population

…, M Gallo, R Bustamante, SL Vargas - Clinical Infectious …, 2010 - academic.oup.com
Background . Increasing reports of Pneumocystis DNA in noninvasive respiratory specimens
from immunocompetent asymptomatic adults and the characteristic lung tropism of …

Synthesis and pharmacological evaluation of a series of dibenzo [a, d] cycloalkenimines as N-methyl-D-aspartate antagonists

…, TA Lyle, JE Thies, CA Magill, SL Varga… - Journal of medicinal …, 1990 - ACS Publications
A series of 73 dibenzo [o, d] cycloalkenimines were synthesized and evaluated fortheir
ability to displace (+)-10, ll-dihydro-5-methyl-5Ff-dibenzo [o, d] cyclohepten-5, 10-imine ([3H]-(+)-…

Total synthesis of an enzyme. V. Preparation of enzymatically active material

…, RF Nutt, DF Veber, RA Vitali, SL Varga… - Journal of the …, 1969 - ACS Publications
Varga, John D. Milkowski H. Joshua, John B. … Varga, J. D. Milkowski, H. … Varga,Theodore
A. Jacob Frederick W. Holly, Robert G. …