Pharmacokinetics and pharmacodynamics of the novel Nrf2 activator omaveloxolone in primates

SA Reisman, SS Gahir, CYI Lee… - Drug Design …, 2019 - Taylor & Francis
Background Omaveloxolone is a synthetic oleanane triterpenoid that pharmacologically
activates Nrf2, a master transcription factor that regulates genes with antioxidative, anti-…

Gestational and pregnane X receptor-mediated regulation of placental ATP-binding cassette drug transporters in mice

SS Gahir, M Piquette-Miller - Drug metabolism and disposition, 2011 - ASPET
The ATP-binding cassette (ABC) drug transporters in the placenta are involved in controlling
the exchange of endogenous and exogenous moieties. Pregnane X receptor (PXR) is a …

[HTML][HTML] The role of PXR genotype and transporter expression in the placental transport of lopinavir in mice

SS Gahir, M Piquette-Miller - Pharmaceutics, 2017 - mdpi.com
Lopinavir (LPV), an antiretroviral protease inhibitor frequently prescribed in HIV-positive
pregnancies, is a substrate of Abcb1 and Abcc2. As differences in placental expression of these …

KE Basin water dispositioning engineering study

GS Hunacek, SS Gahir - 1994 - inis.iaea.org
This engineering study is a feasibility study of KE Basin Water treatment to an acceptable
level and dispositioning the treated water to Columbia River, ground through ETF or to air …

[BOOK][B] PXR-Mediated Regulation of Placental Drug Transporters & Impact on Fetal Exposure to Lopinavir

SS Gahir - 2014 - search.proquest.com
… This chapter is a reprint of “Gahir SS, Piquette-Miller M. Gestational and pregnane X
receptormediated regulation of placental ATP-binding cassette drug transporters in mice. Drug …

[HTML][HTML] A scoping review of the quality and the design of evaluations of mobile health, telehealth, smart pump and monitoring technologies performed in a pharmacy …

D Baines, IK Gahir, A Hussain, AJ Khan… - Frontiers in …, 2018 - frontiersin.org
Background: There is currently a need for high quality evaluations of new mobile health,
telehealth, smart pump and monitoring technologies undertaken in a pharmacy-related setting. …

[HTML][HTML] Abscisic acid-induced stomatal closure: An important component of plant defense against abiotic and biotic stress

P Bharath, S Gahir, AS Raghavendra - Frontiers in Plant Science, 2021 - frontiersin.org
Abscisic acid (ABA) is a stress hormone that accumulates under different abiotic and biotic
stresses. A typical effect of ABA on leaves is to reduce transpirational water loss by closing …

Investigation of journal bearings with nanoparticles mixed lubricant using computational fluid dynamics

GS Gahir, SS Matharu - AIP Conference Proceedings, 2023 - pubs.aip.org
Hydrodynamic journal bearing is one of the most cost-effective and efficient machine elements,
without any external means to maintain lubricant pressure along the periphery of the shaft…

Mechanism of stomatal closure in plants exposed to drought and cold stress

S Agurla, S Gahir, S Munemasa, Y Murata… - Survival strategies in …, 2018 - Springer
Drought is one of the abiotic stresses which impairs the plant growth/development and restricts
the yield of many crops throughout the world. Stomatal closure is a common adaptation …

Process parametric optimization in drilling of CFRP composites using GRA method

T Barik, SK Jena, S Gahir, K Pal, SK Pattnaik - Materials Today …, 2021 - Elsevier
In the modern world, lightweight fibrous composites materials with high mechanical properties
are the first choice for structural design purpose. Excellent mechanical properties and …