User profiles for S. Y. Wong

Shin Yee Wong

Associate Professor Singapore Institute of Technology
Verified email at singaporetech.edu.sg
Cited by 1745

Efficacy of covid-19 vaccines in immunocompromised patients: systematic review and meta-analysis

ARYB Lee, SY Wong, LYA Chai, SC Lee, MX Lee… - Bmj, 2022 - bmj.com
… Ainsley Ryan Yan Bin Lee,1 Shi Yin Wong,1 Louis Yi Ann Chai,2,3,4,5 Soo Chin Lee,6,7
Matilda Xinwei Lee,6 Mark Dhinesh Muthiah,8,9 Sen Hee Tay,10 Chong Boon Teo,1 Benjamin …

Polymer systems for gene delivery—past, present, and future

SY Wong, JM Pelet, D Putnam - Progress in Polymer Science, 2007 - Elsevier
Gene therapy has long sought to treat disease by delivering therapeutic genes to diseased
cells. However, its widespread clinical use has faltered in the face of several challenges, …

Toxoplasmosis in pregnancy

SY Wong, JS Remington - Clinical infectious diseases, 1994 - JSTOR
Acute acquired toxoplasma infection in a pregnant woman may result in a tragic outcome for
her offspring. Transmission to the fetus has been limited almost solely to those women who …

On-demand continuous-flow production of pharmaceuticals in a compact, reconfigurable system

…, DR Snead, T Stelzer, N Weeranoppanant, SY Wong… - Science, 2016 - science.org
Pharmaceutical manufacturing typically uses batch processing at multiple locations.
Disadvantages of this approach include long production times and the potential for supply chain …

In vivo genome editing restores haemostasis in a mouse model of haemophilia

H Li, V Haurigot, Y Doyon, T Li, SY Wong, AS Bhagwat… - Nature, 2011 - nature.com
Editing of the human genome to correct disease-causing mutations is a promising approach
for the treatment of genetic disorders. Genome editing improves on simple gene-…

Intrinsically fluorescent carbon dots with tunable emission derived from hydrothermal treatment of glucose in the presence of monopotassium phosphate

ZC Yang, M Wang, AM Yong, SY Wong… - Chemical …, 2011 - pubs.rsc.org
A facile method is developed to synthesize intrinsically fluorescent carbon dots by hydrothermal
treatment of glucose in the presence of monopotassium phosphate. The fluorescence …

Primary cilia can both mediate and suppress Hedgehog pathway–dependent tumorigenesis

SY Wong, AD Seol, PL So, AN Ermilov… - Nature medicine, 2009 - nature.com
Primary cilia are present on most mammalian cells and are implicated in transducing
Hedgehog (Hh) signals during development; however, the prevalence of cilia on human tumors …

[HTML][HTML] Depression, anxiety and symptoms of stress among baccalaureate nursing students in Hong Kong: a cross-sectional study

T Cheung, SY Wong, KY Wong, LY Law, K Ng… - International journal of …, 2016 - mdpi.com
This study examines the prevalence of depression, anxiety and symptoms of stress among
baccalaureate nursing students in Hong Kong. Recent epidemiological data suggest that the …

Rag mutations reveal robust alternative end joining

…, RL Wendland, L Deriano, X Cui, IA Klein, SY Wong… - Nature, 2007 - nature.com
Mammalian cells repair DNA double-strand breaks (DSBs) through either homologous
recombination or non-homologous end joining (NHEJ). V(D)J recombination, a cut-and-paste …

[PDF][PDF] Basal cell carcinoma preferentially arises from stem cells within hair follicle and mechanosensory niches

…, CK Bichakjian, NL Ward, AA Dlugosz, SY Wong - Cell stem cell, 2015 - cell.com
Basal cell carcinoma (BCC) is characterized by frequent loss of PTCH1, leading to constitutive
activation of the Hedgehog pathway. Although the requirement for Hedgehog in BCC is …