CYP3A activity and expression in nonalcoholic fatty liver disease

SJ Woolsey, SE Mansell, RB Kim, RG Tirona… - Drug Metabolism and …, 2015 - ASPET
Nonalcoholic fatty liver disease (NAFLD) is the leading cause of liver disease in the Western
world, given its association with obesity, type 2 diabetes, and dyslipidemia. Medications are …

Relationships between Endogenous Plasma Biomarkers of Constitutive Cytochrome P 450 3 A Activity and Single‐Time‐Point Oral Midazolam Microdose Phenotype …

SJ Woolsey, MD Beaton, YH Choi… - Basic & clinical …, 2016 - Wiley Online Library
Due to high basal interindividual variation in cytochrome P 450 3 A ( CYP 3 A ) activity and
susceptibility to drug interactions, there has been interest in the application of efficient probe …

A fibroblast growth factor 21–pregnane X receptor pathway downregulates hepatic CYP3A4 in nonalcoholic fatty liver disease

SJ Woolsey, MD Beaton, SE Mansell… - Molecular …, 2016 - ASPET
Nonalcoholic fatty liver disease (NAFLD) alters drug response. We previously reported that
NAFLD is associated with reduced in vivo CYP3A drug-metabolism activity and hepatic …

[BOOK][B] Cytochrome P450 3A4 Expression and Regulation in Non-Alcoholic Fatty Liver Disease

SJ Woolsey - 2015 - search.proquest.com
Non-alcoholic fatty liver disease (NAFLD) is defined as lipid accumulation within hepatocytes
(steatosis) in the absence of excess alcohol consumption. It is the most common liver …

Regulation of Cytochrome P450 3A4 in Non-Alcoholic Fatty Liver Disease by Fibroblast Growth Factor 21: 1481

SJ Woolsey, JA Tanner, I Gong, MD Beaton, RB Kim… - Hepatology, 2012 - journals.lww.com
Background. Non-alcoholic fatty liver disease (NAFLD) affects approximately one third of
adults. Interestingly, while many drugs used by patients with NAFLD are eliminated from the …

[PDF][PDF] Cytochrome P450 3A Activity and Expression in Non-Alcoholic Fatty Liver Disease

SJ Woolsey, SE Mansell, RB Kim, RG Tirona… - schulich.uwo.ca
DMD # 65979 1 Cytochrome P450 3A Activity and Expression in Non-Alcoholic Fatty Liver
Disease Sarah J. … healthy control subjects collected from previous studies reported by Woolsey …

[BOOK][B] The impact of 9/11 on politics and war: The day that changed everything?

RJ Woolsey - 2009 - books.google.com
The Impact of 9/11 on Politics and War is the first volume of the six-volume series The Day
that Changed Everything? edited by Matthew J. Morgan. The series brings together from a …

Liberating People from Psychiatric Diagnoses 2: Exploring Severe Mental, Behavioral, and Emotional Disturbances Through Case Study

SE Wong, JE Woolsey - Ethical Human Psychology and …, 2022 - connect.springerpub.com
The second article in a series, this case study demonstrates how psychiatric diagnoses and
treatment can ignore social, environmental, and personal history factors that likely caused a …

[BOOK][B] Symbolic Mythology and Translation of a Lost and Forgotten Language

JM Woolsey - 1917 - books.google.com
Metaphor is confined to a single expression. Animism belonged to a primitive form of
religious superstition, when animals and plants were possessed of souls and the tree had an …

The Casual Dress of the 1950s Woman and the Casual Dress of Today's Woman

J Woolsey - 2019 - digitalcommons.liberty.edu
The casual dress of American women has changed dramatically from the 1950s to the present.
In the 1950s, the style was undeniably feminine, with fitted waists and full skirts ending …