[HTML][HTML] Rabbit serum paraoxonase 3 (PON3) is a high density lipoprotein-associated lactonase and protects low density lipoprotein against oxidation
…, PL Stetson, CE Watson, SS Billecke… - Journal of Biological …, 2000 - ASBMB
The paraoxonase gene family contains at least three members: PON1, PON2, andPON3.
The physiological roles of the corresponding gene products are still uncertain. Until recently, …
The physiological roles of the corresponding gene products are still uncertain. Until recently, …
Pheochromocytoma presenting with Takotsubo syndrome
…, P Czako, S Rosenblatt, SS Billecke - Journal of …, 2010 - Wiley Online Library
The clinical presentation of Takotsubo syndrome, or apical ballooning syndrome, resembles
an extensive anterolateral myocardial infarction with chest pain symptoms and …
an extensive anterolateral myocardial infarction with chest pain symptoms and …
[HTML][HTML] hsp90 is required for heme binding and activation of apo-neuronal nitric-oxide synthase: geldanamycin-mediated oxidant generation is unrelated to any …
SS Billecke, AT Bender, KC Kanelakis… - Journal of Biological …, 2002 - ASBMB
It is established that neuronal NO synthase (nNOS) is associated with the chaperone hsp90,
although the functional role for this interaction has not been defined. We have discovered …
although the functional role for this interaction has not been defined. We have discovered …
Usefulness of breast arterial calcium detected on mammography for predicting coronary artery disease or cardiovascular events in women with angina pectoris and/or …
N Penugonda, SS Billecke, MW Yerkey… - The American journal of …, 2010 - Elsevier
Breast arterial calcium (BAC) has been suggested as a marker and predictor of cardiovascular
risk and coronary artery disease (CAD). However, an association between BAC and …
risk and coronary artery disease (CAD). However, an association between BAC and …
Estrogen esters as substrates for human paraoxonases
JF Teiber, SS Billecke, BN La Du… - Archives of biochemistry …, 2007 - Elsevier
Mammalian paraoxonases (PONs 1, 2 and 3) are a highly conserved family of esterases, with
uncertain physiological functions and natural substrates. Here we characterize the ability …
uncertain physiological functions and natural substrates. Here we characterize the ability …
Asymmetrical dimethylarginine plasma clearance persists after acute total nephrectomy in rats
…, SE Whitesall, MC Lloyd, SS Billecke… - American Journal …, 2006 - journals.physiology.org
Elevated plasma concentrations of symmetrical dimethylarginine (SDMA) and asymmetrical
dimethylarginine (ADMA) are repeatedly associated with kidney failure. Both ADMA and …
dimethylarginine (ADMA) are repeatedly associated with kidney failure. Both ADMA and …
[HTML][HTML] The role of hsp90 in heme-dependent activation of apo-neuronal nitric-oxide synthase
SS Billecke, DI Draganov, Y Morishima… - Journal of Biological …, 2004 - ASBMB
Like other nitric-oxide synthase (NOS) enzymes, neuronal NOS (nNOS) turnover and activity
are regulated by the ubiquitous protein chaperone hsp90. We have shown previously that …
are regulated by the ubiquitous protein chaperone hsp90. We have shown previously that …
Proteolytic degradation of nitric oxide synthase: effect of inhibitors and role of hsp90-based chaperones
…, ER Lowe, AC Everett, AY Dunbar, SS Billecke - … of Pharmacology and …, 2003 - ASPET
Nitric oxide synthase (NOS) is a highly regulated enzyme that produces nitric oxide, a critical
messenger in many physiological processes. In this perspective, we explore the role of …
messenger in many physiological processes. In this perspective, we explore the role of …
Contribution of whole blood to the control of plasma asymmetrical dimethylarginine
SS Billecke, LA Kitzmiller, JJ Northrup… - American Journal …, 2006 - journals.physiology.org
The endogenous nitric oxide (NO) synthase (NOS) inhibitor asymmetrical dimethylarginine (ADMA)
is elevated in many patients and may contribute to the initiation and progression of …
is elevated in many patients and may contribute to the initiation and progression of …
Ubiquitination and degradation of neuronal nitric-oxide synthase in vitro: dimer stabilization protects the enzyme from proteolysis
…, Y Kamada, GJ Jenkins, ER Lowe, SS Billecke… - Molecular …, 2004 - ASPET
It is established that neuronal NO synthase (nNOS) is ubiquitinated and proteasomally degraded.
The metabolism-based inactivation of nNOS and the inhibition of heat shock protein 90 …
The metabolism-based inactivation of nNOS and the inhibition of heat shock protein 90 …