It has been proposed that low density lipoprotein (LDL) must undergo oxidative modification
before it can give rise to foam cells, the key component of the fatty streak lesion of …

Members of the vascular endothelial growth factor (VEGF) family are among the most
powerful modulators of vascular biology. They regulate vasculogenesis, angiogenesis, and …

© The American Society of Gene & Cell Therapy editorial and predictability can be achieved
in the process of regulatory evaluation and approval. The Glybera saga also highlights …

Two decades after the initial gene therapy trials and more than 1700 approved clinical trials
worldwide we not only have gained much new information and knowledge regarding gene …

Angiogenesis is the process by which new blood vessels are formed from existing vessels.
The vascular endothelial growth factors (VEGFs) are considered as key molecules in the …

Many solid tumors produce vascular endothelial growth factor C (VEGF-C), and its receptor,
VEGFR-3, is expressed in tumor blood vessels. To study the role of VEGF-C in tumorigenesis…

The lymphatic vasculature transports extravasated tissue fluid, macromolecules and cells
back into the blood circulation. Recent reports have focused on the molecular mechanisms …

Angiogenesis, the growth of new blood vessels from pre-existing vasculature, is a key
process in several pathological conditions, including tumour growth and age-related macular …

Lymphatic vessels are essential for fluid homeostasis, immune surveillance and fat adsorption,
and also serve as a major route for tumor metastasis in many types of cancer. We found …

Background— Catheter-based intracoronary vascular endothelial growth factor (VEGF) gene
transfer is a potential treatment for coronary heart disease. However, only limited data are …