User profiles for Shota Nakamura

Shota Nakamura

Department of Infection Metagenomics, Research Institute for Microbial Diseases, Osaka …
Verified email at gen-info.osaka-u.ac.jp
Cited by 17130

Dysbiosis contributes to arthritis development via activation of autoreactive T cells in the intestine

…, N Sakaguchi, H Kayama, S Nakamura… - Arthritis & …, 2016 - Wiley Online Library
Objective The intestinal microbiota is involved in the pathogenesis of arthritis. Altered microbiota
composition has been demonstrated in patients with rheumatoid arthritis (RA). However…

[HTML][HTML] The lipid mediator protectin D1 inhibits influenza virus replication and improves severe influenza

…, T Watanebe, S Sakabe, T Daidoji, S Nakamura… - Cell, 2013 - cell.com
Influenza A viruses are a major cause of mortality. Given the potential for future lethal pandemics,
effective drugs are needed for the treatment of severe influenza such as that caused by …

[HTML][HTML] Oral pathobiont induces systemic inflammation and metabolic changes associated with alteration of gut microbiota

…, MI Ryder, K Gotoh, D Motooka, S Nakamura… - Scientific reports, 2014 - nature.com
Periodontitis has been implicated as a risk factor for metabolic disorders such as type 2
diabetes, atherosclerotic vascular diseases and non-alcoholic fatty liver disease. Although …

Aldosterone production is activated in failing ventricle in humans

…, K Kugiyama, E Harada, M Nakayama, S Nakamura… - Circulation, 2001 - Am Heart Assoc
Background—Recent reports have indicated that aldosterone is produced in extra-adrenal
tissues in animals. The present study was designed to examine whether aldosterone is …

Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment

…, R Kawakami, K Yasuda, D Motooka, S Nakamura… - Nature …, 2017 - nature.com
Most Foxp3+ regulatory T (T reg) cells develop in the thymus as a functionally mature T cell
subpopulation specialized for immune suppression. Their cell fate appears to be determined …

[HTML][HTML] Direct metagenomic detection of viral pathogens in nasal and fecal specimens using an unbiased high-throughput sequencing approach

S Nakamura, CS Yang, N Sakon, M Ueda, T Tougan… - PloS one, 2009 - journals.plos.org
With the severe acute respiratory syndrome epidemic of 2003 and renewed attention on avian
influenza viral pandemics, new surveillance systems are needed for the earlier detection …

[HTML][HTML] Engineered ACE2 receptor therapy overcomes mutational escape of SARS-CoV-2

…, E Ohgitani, O Mazda, D Motooka, S Nakamura… - Nature …, 2021 - nature.com
SARS-CoV-2 has mutated during the global pandemic leading to viral adaptation to medications
and vaccinations. Here we describe an engineered human virus receptor, ACE2, by …

[HTML][HTML] Current trends in thoracic surgery

TF Chen-Yoshikawa, T Fukui, S Nakamura… - Nagoya Journal of …, 2020 - ncbi.nlm.nih.gov
Thoracic surgery has evolved drastically in recent years. Although thoracic surgeons mainly
deal with tumorous lesion in the lungs, mediastinum, and pleura, they also perform lung …

[HTML][HTML] Gut microbiota of healthy and malnourished children in Bangladesh

S Monira, S Nakamura, K Gotoh, K Izutsu… - Frontiers in …, 2011 - frontiersin.org
Poor health and malnutrition in preschool children are longstanding problems in Bangladesh.
Gut microbiota plays a tremendous role in nutrient absorption and determining the state of …

[HTML][HTML] Plasmodium cynomolgi genome sequences provide insight into Plasmodium vivax and the monkey malaria clade

SI Tachibana, SA Sullivan, S Kawai, S Nakamura… - Nature …, 2012 - nature.com
P. cynomolgi, a malaria-causing parasite of Asian Old World monkeys, is the sister taxon of
P. vivax, the most prevalent malaria-causing species in humans outside of Africa. Because P. …