Effects of AGN 192024, a new ocular hypotensive agent, on aqueous dynamics

RF Brubaker, EO Schoff, CB Nau, SP Carpenter… - American journal of …, 2001 - Elsevier
PURPOSE: To determine the mechanism of intraocular pressure lowering for the Ocular
Hypotensive Lipid, AGN 192024 (Allergan, Inc, Irvine, California). METHODS: Twenty-five …

Safety and feasibility of convection-enhanced delivery of Cotara for the treatment of malignant glioma: initial experience in 51 patients

…, RL Jensen, AL Asher, BW Wessels, SP Carpenter… - …, 2005 - journals.lww.com
… A nominal treatment absorbed dose delivered to a patient-specific CTV was set at 15,000
cGy on the basis of intracystic 32 P experience ( 23 ). The amount of activity needed to deliver …

Human hepatocytes express an array of proinflammatory cytokines after agonist stimulation or bacterial invasion

…, MB Dwinell, SP Carpenter… - American Journal …, 1997 - journals.physiology.org
Inflammatory cells infiltrate the liver in response to microbial infection or hepatic injury. To
assess the potential role hepatocytes may play in initiating or amplifying the acute …

[PDF][PDF] Expression, induction, and catalytic activity of the ethanol-inducible cytochrome P450 (CYP2E1) in human fetal liver and hepatocytes.

SP Carpenter, JM Lasker, JL Raucy - Molecular pharmacology, 1996 - researchgate.net
The mechanisms responsible for ethanol-mediated teratogenesis have not been resolved.
However, possible etiologies indude the local formation of the teratogen acetaldehyde or …

24-Hour IOP control with once-daily bimatoprost, timolol gel-forming solution, or latanoprost: a 1-month, randomized, comparative clinical trial

TR Walters, HB DuBiner, SP Carpenter, B Khan… - Survey of …, 2004 - Elsevier
PURPOSE: To compare the efficacy and safety of once-daily (QD) bimatoprost, latanoprost,
and timolol gel-forming solution in providing 24-hour intraocular pressure (IOP) control. …

Results of a phase 1 study of AME-133v (LY2469298), an Fc-engineered humanized monoclonal anti-CD20 antibody, in FcγRIIIa-genotyped patients with previously …

…, DM Cronier, NH Dang, SP Carpenter… - Clinical cancer …, 2012 - AACR
Purpose: AME-133v is a humanized monoclonal antibody engineered to have increased
affinity to CD20 and mediate antibody-dependent cell-mediated cytotoxicity (ADCC) better than …

131I-chTNT-1/B mAb: tumour necrosis therapy for malignant astrocytic glioma

WR Shapiro, SP Carpenter, K Roberts… - Expert opinion on …, 2006 - Taylor & Francis
Treatment of malignant glioma is therapeutically challenging. Despite improvements in
neurosurgery, radiotherapy and chemotherapy, few patients diagnosed with anaplastic …

Human lymphocyte cytochrome P450 2E1, a putative marker for alcohol-mediated changes in hepatic chlorzoxazone activity

…, S Arora, DE Johnston, JL Omdahl, SP Carpenter - Drug Metabolism and …, 1997 - ASPET
Cytochrome P450 (CYP) 2E1 is implicated in a variety of chemically initiated hepatotoxicities,
including alcoholic liver disease. These pathological conditions arise from increased …

Phase 1/2 study of ocaratuzumab, an Fc-engineered humanized anti-CD20 monoclonal antibody, in low-affinity FcγRIIIa patients with previously treated follicular …

…, NH Dang, KA Foon, SP Carpenter… - Leukemia & …, 2015 - Taylor & Francis
This phase 2 study assessed the safety and efficacy of ocaratuzumab, a humanized anti-CD20
monoclonal antibody. Fifty patients with previously treated follicular lymphoma (FL) and a …

Use of Lymphocytes for Assessing Ethanol‐Mediated Alterations in the Expression of Hepatic Cytochrome P4502E1

…, G Curley, SP Carpenter - Alcoholism: Clinical and …, 1995 - Wiley Online Library
The ethanol‐inducible cytochrome P4502E1 (2E1) is involved in the bioactivation of numerous
hepatotoxins and hepatocarcinogens. Because high levels of expression may enhance …