Mice lacking the metalloprotease-disintegrin MDC9 (ADAM9) have no evident major abnormalities during development or adult life
G Weskamp, H Cai, TA Brodie… - … and cellular biology, 2002 - Am Soc Microbiol
MDC9 (ADAM9/meltrin γ) is a widely expressed and catalytically active metalloprotease-disintegrin
protein that has been implicated in the ectodomain cleavage of heparin-binding …
protein that has been implicated in the ectodomain cleavage of heparin-binding …
Potential role for ADAM15 in pathological neovascularization in mice
ADAM15 (named for a disintegrin and metalloprotease 15, metargidin) is a membrane-anchored
glycoprotein that has been implicated in cell-cell or cell-matrix interactions and in the …
glycoprotein that has been implicated in cell-cell or cell-matrix interactions and in the …
Dietary glycine prevents peptidoglycan polysaccharide-induced reactive arthritis in the rat: role for glycine-gated chloride channel
…, SA Stimpson, HM Pink, TA Brodie… - Infection and …, 2001 - Am Soc Microbiol
Peptidoglycan polysaccharide (PG-PS) is a primary structural component of bacterial cell
walls and causes rheumatoid-like arthritis in rats. Recently, glycine has been shown to be a …
walls and causes rheumatoid-like arthritis in rats. Recently, glycine has been shown to be a …
Some aspects of tick-borne diseases of British sheep.
TA Brodie, PH Holmes, GM Urquhart - The Veterinary Record, 1986 - europepmc.org
The significance of tick-borne fever (TBF) and other tick-borne diseases of British sheep are
reviewed. Experimental and field studies were carried out to clarify the role of TBF as a …
reviewed. Experimental and field studies were carried out to clarify the role of TBF as a …
Inhibition of tumor necrosis factor-α (TNF-α) production and arthritis in the rat by GW3333, a dual inhibitor of TNF-α-converting enzyme and matrix metalloproteinases
…, B Beaudet, DM Bickett, V Boncek, TA Brodie… - … of Pharmacology and …, 2001 - ASPET
Tumor necrosis factor-α (TNF)-converting enzyme (TACE) cleaves the precursor form of TNF,
allowing the mature form to be secreted into the extracellular space. GW3333, a dual …
allowing the mature form to be secreted into the extracellular space. GW3333, a dual …
Homeostatic effects of the metalloproteinase disintegrin ADAM15 in degenerative cartilage remodeling
BB Böhm, T Aigner, B Roy, TA Brodie… - Arthritis & …, 2005 - Wiley Online Library
Objective The membrane‐anchored metalloproteinase disintegrin ADAM15 is up‐regulated
in osteoarthritis and has been implicated in proteolysis and cell–matrix interactions. To …
in osteoarthritis and has been implicated in proteolysis and cell–matrix interactions. To …
Effects of the cFMS kinase inhibitor 5-(3-methoxy-4-((4-methoxybenzyl) oxy) benzyl) pyrimidine-2, 4-diamine (GW2580) in normal and arthritic rats
…, JT Hutchins, SD Chamberlain, TA Brodie - … of Pharmacology and …, 2008 - ASPET
The cFMS (cellular homolog of the V-FMS oncogene product of the Susan McDonough strain
of feline sarcoma virus) (Proc Natl Acad Sci USA 83:3331–3335, 1986) kinase inhibitor 5-(3…
of feline sarcoma virus) (Proc Natl Acad Sci USA 83:3331–3335, 1986) kinase inhibitor 5-(3…
Adverse vacuolation in multiple tissues in cynomolgus monkeys following repeat-dose administration of a PEGylated protein
…, P Mansell, MJ Graziano, RS Mangipudy, TA Brodie… - Toxicology Letters, 2019 - Elsevier
PEGylation is considered a safe mechanism to enhance the pharmacokinetics (PK) and
pharmacodynamics (PD) of biotherapeutics. Previous studies using PEGylation as a PK …
pharmacodynamics (PD) of biotherapeutics. Previous studies using PEGylation as a PK …
Response of sheep to experimental concurrent infection with tick-borne fever (Cytoecetes phagocytophila) and louping-ill virus
HW Reid, D Buxton, I Pow, TA Brodie… - Research in veterinary …, 1986 - Elsevier
The pathogenesis of concurrent Cytoecetes phagocytophila and louping-ill virus infection
was studied in two experiments. In the first experiment 18 four- to seven-year-old rams were …
was studied in two experiments. In the first experiment 18 four- to seven-year-old rams were …
Attitude toward school and academic achievement
TA Brodie Jr - The Personnel and Guidance Journal, 1964 - Wiley Online Library
Two groups of urban eleventh graders were contrasted in their attitudes toward school by
means of a specially developed poll. Classified as “satisfied” and “dissatisfied” with school, …
means of a specially developed poll. Classified as “satisfied” and “dissatisfied” with school, …