Indole and tryptophan metabolism: endogenous and dietary routes to Ah receptor activation
TD Hubbard, IA Murray, GH Perdew - Drug Metabolism and Disposition, 2015 - ASPET
The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor recognized for
its role in xenobiotic metabolism. The physiologic function of AHR has expanded to include …
its role in xenobiotic metabolism. The physiologic function of AHR has expanded to include …
Persistent organic pollutants modify gut microbiota–host metabolic homeostasis in mice through aryl hydrocarbon receptor activation
…, N Tanaka, PB Smith, TD Hubbard… - Environmental …, 2015 - ehp.niehs.nih.gov
Background Alteration of the gut microbiota through diet and environmental contaminants may
disturb physiological homeostasis, leading to various diseases including obesity and type …
disturb physiological homeostasis, leading to various diseases including obesity and type …
[HTML][HTML] Adaptation of the human aryl hydrocarbon receptor to sense microbiota-derived indoles
TD Hubbard, IA Murray, WH Bisson, TS Lahoti… - Scientific reports, 2015 - nature.com
… was followed by the addition of 150 μL of lysis buffer, chemiluminescence was determined
by mixing 50 μL of lysate plus 50 μL of luciferase reporter substrate and measured on a TD-…
by mixing 50 μL of lysate plus 50 μL of luciferase reporter substrate and measured on a TD-…
Reputation as a Benefit and a Burden? How Stakeholders' Organizational Identification Affects the Role of Reputation Following a Negative Event
Research about the effects of an organization’s general reputation following a negative event
remains equivocal: Some studies have found that high reputation is a benefit because of …
remains equivocal: Some studies have found that high reputation is a benefit because of …
Higher highs and lower lows: The role of corporate social responsibility in CEO dismissal
TD Hubbard, DM Christensen… - Strategic Management …, 2017 - Wiley Online Library
Research summary: Investing a firm's resources in corporate social responsibility ( CSR )
initiatives remains a contentious issue. While research suggests firm financial performance is …
initiatives remains a contentious issue. While research suggests firm financial performance is …
Dietary broccoli impacts microbial community structure and attenuates chemically induced colitis in mice in an Ah receptor dependent manner
TD Hubbard, IA Murray, RG Nichols, K Cassel… - Journal of functional …, 2017 - Elsevier
Consumption of broccoli mediates numerous chemo-protective benefits through the intake
of phytochemicals, some of which modulate aryl hydrocarbon receptor (AHR) activity. …
of phytochemicals, some of which modulate aryl hydrocarbon receptor (AHR) activity. …
Safe bets or hot hands? How status and celebrity influence strategic alliance formations by newly public firms
Social approval assets derive their value from favorable stakeholder perceptions. Past
research has focused primarily on their role as signals that reduce stakeholders’ perceived …
research has focused primarily on their role as signals that reduce stakeholders’ perceived …
Divergent Ah receptor ligand selectivity during hominin evolution
TD Hubbard, IA Murray, WH Bisson… - Molecular Biology …, 2016 - academic.oup.com
We have identified a fixed nonsynonymous sequence difference between humans (Val381;
derived variant) and Neandertals (Ala381; ancestral variant) in the ligand-binding domain of …
derived variant) and Neandertals (Ala381; ancestral variant) in the ligand-binding domain of …
Frozen debris lobe morphology and movement: an overview of eight dynamic features, southern Brooks Range, Alaska
…, JM Simpson, RP Daanen, TD Hubbard - The …, 2016 - tc.copernicus.org
Frozen debris lobes (FDLs) are elongated, lobate permafrost features that mostly move
through shear in zones near their bases. We present a comprehensive overview of eight FDLs …
through shear in zones near their bases. We present a comprehensive overview of eight FDLs …
Unintended consequences: Information releases and CEO stock option grants
Scholars, regulators, and practitioners have long struggled with challenges emanating from
the separation of ownership and control of modern corporations. Agency theory typically …
the separation of ownership and control of modern corporations. Agency theory typically …