User profiles for T. Haarmann-Stemmann

Haarmann-Stemmann

Group Leader, IUF Duesseldorf, Germany
Verified email at uni-duesseldorf.de
Cited by 3371

An introduction to the molecular basics of aryl hydrocarbon receptor biology

J Abel, T Haarmann-Stemmann - 2010 - degruyter.com
… Only a few natural compounds such as the b-carboline alkaloid rutaecarpine found in
Szechuan pepper (HaarmannStemmann et al., 2010) and some indole derivatives exhibit affinities …

[HTML][HTML] The aryl hydrocarbon receptor as a target of environmental stressors–Implications for pollution mediated stress and inflammatory responses

…, LS Van Winkle, C Esser, T Haarmann-Stemmann - Redox biology, 2020 - Elsevier
… Van Winkle a c , Charlotte Esser d 1 , Thomas Haarmann-Stemmann d 1 … Organic fractions
of ambient urban dust Murine T cell differentiation in vitro Enhancement of Th17 differentiation …

Growth factors, cytokines and their receptors as downstream targets of arylhydrocarbon receptor (AhR) signaling pathways

T Haarmann-Stemmann, H Bothe, J Abel - Biochemical pharmacology, 2009 - Elsevier
… triggers the differentiation of naive CD4 + T cells into T reg and T H 17 cells in a ligand-specific
manner [94], [95]. The persistent, long-acting AhR agonist TCDD induced functional …

[HTML][HTML] Cross-talk between aryl hydrocarbon receptor and the inflammatory response: a role for nuclear factor-κB

…, WLW Chang, D Wu, T Haarmann-Stemmann… - Journal of Biological …, 2014 - ASBMB
The aryl hydrocarbon receptor (AhR) is involved in the regulation of immune responses, T-cell
differentiation, and immunity. Here, we show that inflammatory stimuli such as LPS induce …

Functions of the aryl hydrocarbon receptor in the skin

…, H Weighardt, T Haarmann-Stemmann… - Seminars in …, 2013 - Springer
… cells (DCs) of the skin, αβ T cells, and T cells with an invariant γδ T cell receptor (1–5 %).
The latter are often referred to as dendritic epidermal T cells due to their shape. Every LC and …

Functions of the aryl hydrocarbon receptor (AHR) beyond the canonical AHR/ARNT signaling pathway

…, KM Rolfes, CFA Vogel, T Haarmann-Stemmann - Biochemical …, 2023 - Elsevier
… The critical relevance of AHR for the adverse health effects induced by dioxins is illustrated
by several chemical incidents, such as the Seveso disaster in 1976, an explosion of a 2,4,5-T

[HTML][HTML] The Janus-faced role of aryl hydrocarbon receptor signaling in the skin: consequences for prevention and treatment of skin disorders

T Haarmann-Stemmann, C Esser… - Journal of Investigative …, 2015 - Elsevier
… Author links open overlay panel Thomas Haarmann-Stemmann 1 , Charlotte Esser 1 , Jean
… interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27 …

[HTML][HTML] Monoterpenoid aryl hydrocarbon receptor allosteric antagonists protect against ultraviolet skin damage in female mice

…, M Soural, KM Rolfes, T Haarmann-Stemmann… - Nature …, 2023 - nature.com
The human aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that is
a pivotal regulator of human physiology and pathophysiology. Allosteric inhibition of AhR …

The aryl hydrocarbon receptor (AhR) mediates resistance to apoptosis induced in breast cancer cells

…, T Ito, C Sweeney, T Haarmann-Stemmann… - Pesticide biochemistry …, 2015 - Elsevier
The aryl hydrocarbon receptor (AhR) is well known as a ligand binding transcription factor
regulating various biological effects. Previously we have shown that long-term exposure to …

Modulation of CYP1A1 metabolism: From adverse health effects to chemoprevention and therapeutic options

M Mescher, T Haarmann-Stemmann - Pharmacology & therapeutics, 2018 - Elsevier
… Author links open overlay panel Melina Mescher , Thomas Haarmann-Stemmann … the
expression of IL-17 in human primary CD4 + T helper cells. Co-treatment with the ligand-selective …